FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977290961> ?p ?o ?g. }

• W1977290961 endingPage "1006" @default.
• W1977290961 startingPage "997" @default.
• W1977290961 abstract "A high-throughput approach and platform using 15 min reversed-phase capillary liquid chromatography (RPLC) separations in conjunction with ion mobility spectrometry-mass spectrometry (IMS-MS) measurements was evaluated for the rapid analysis of complex proteomics samples. To test the separation quality of the short LC gradient, a sample was prepared by spiking 20 reference peptides at varying concentrations from 1 ng/mL to 10 μg/mL into a tryptic digest of mouse blood plasma and analyzed with both a LC-Linear Ion Trap Fourier Transform (FT) MS and LC-IMS-TOF MS. The LC-FT MS detected 13 out of the 20 spiked peptides that had concentrations ≥100 ng/mL. In contrast, the drift time selected mass spectra from the LC-IMS-TOF MS analyses yielded identifications for 19 of the 20 peptides with all spiking levels present. The greater dynamic range of the LC-IMS-TOF MS system could be attributed to two factors. First, the LC-IMS-TOF MS system enabled drift time separation of the low concentration spiked peptides from the high concentration mouse peptide matrix components, reducing signal interference and background, and allowing species to be resolved that would otherwise be obscured by other components. Second, the automatic gain control (AGC) in the linear ion trap of the hybrid FT MS instrument limits the number of ions that are accumulated to reduce space charge effects and achieve high measurement accuracy, but in turn limits the achievable dynamic range compared to the IMS-TOF instrument." @default.
• W1977290961 created "2016-06-24" @default.
• W1977290961 creator A5022565043 @default.
• W1977290961 creator A5023982706 @default.
• W1977290961 creator A5027231249 @default.
• W1977290961 creator A5027451804 @default.
• W1977290961 creator A5027769343 @default.
• W1977290961 creator A5028794135 @default.
• W1977290961 creator A5031727021 @default.
• W1977290961 creator A5052184745 @default.
• W1977290961 creator A5060603552 @default.
• W1977290961 creator A5062391734 @default.
• W1977290961 creator A5077265846 @default.
• W1977290961 creator A5077796292 @default.
• W1977290961 creator A5081682571 @default.
• W1977290961 creator A5082530337 @default.
• W1977290961 date "2010-01-11" @default.
• W1977290961 modified "2023-10-09" @default.
• W1977290961 title "An LC-IMS-MS Platform Providing Increased Dynamic Range for High-Throughput Proteomic Studies" @default.
• W1977290961 cites W1597678601 @default.
• W1977290961 cites W1665864650 @default.
• W1977290961 cites W1965993495 @default.
• W1977290961 cites W1986249771 @default.
• W1977290961 cites W1993760841 @default.
• W1977290961 cites W1994486619 @default.
• W1977290961 cites W1996938167 @default.
• W1977290961 cites W2004276491 @default.
• W1977290961 cites W2008916791 @default.
• W1977290961 cites W2014228969 @default.
• W1977290961 cites W2021824269 @default.
• W1977290961 cites W2022054869 @default.
• W1977290961 cites W2023096047 @default.
• W1977290961 cites W2025733760 @default.
• W1977290961 cites W2032659860 @default.
• W1977290961 cites W2032961810 @default.
• W1977290961 cites W2033883485 @default.
• W1977290961 cites W2037919844 @default.
• W1977290961 cites W2040308794 @default.
• W1977290961 cites W2050226999 @default.
• W1977290961 cites W2059121099 @default.
• W1977290961 cites W2060933011 @default.
• W1977290961 cites W2061991716 @default.
• W1977290961 cites W2066943304 @default.
• W1977290961 cites W2068565992 @default.
• W1977290961 cites W2075581208 @default.
• W1977290961 cites W2078492636 @default.
• W1977290961 cites W2092612030 @default.
• W1977290961 cites W2094495776 @default.
• W1977290961 cites W2101938218 @default.
• W1977290961 cites W2104786760 @default.
• W1977290961 cites W2107672801 @default.
• W1977290961 cites W2128084205 @default.
• W1977290961 cites W2152321851 @default.
• W1977290961 cites W2162681116 @default.
• W1977290961 cites W2169113064 @default.
• W1977290961 cites W2172116519 @default.
• W1977290961 doi "https://doi.org/10.1021/pr900888b" @default.
• W1977290961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2819092" @default.
• W1977290961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20000344" @default.
• W1977290961 hasPublicationYear "2010" @default.
• W1977290961 type Work @default.
• W1977290961 sameAs 1977290961 @default.
• W1977290961 citedByCount "118" @default.
• W1977290961 countsByYear W19772909612012 @default.
• W1977290961 countsByYear W19772909612013 @default.
• W1977290961 countsByYear W19772909612014 @default.
• W1977290961 countsByYear W19772909612015 @default.
• W1977290961 countsByYear W19772909612016 @default.
• W1977290961 countsByYear W19772909612017 @default.
• W1977290961 countsByYear W19772909612018 @default.
• W1977290961 countsByYear W19772909612019 @default.
• W1977290961 countsByYear W19772909612020 @default.
• W1977290961 countsByYear W19772909612021 @default.
• W1977290961 countsByYear W19772909612022 @default.
• W1977290961 countsByYear W19772909612023 @default.
• W1977290961 crossrefType "journal-article" @default.
• W1977290961 hasAuthorship W1977290961A5022565043 @default.
• W1977290961 hasAuthorship W1977290961A5023982706 @default.
• W1977290961 hasAuthorship W1977290961A5027231249 @default.
• W1977290961 hasAuthorship W1977290961A5027451804 @default.
• W1977290961 hasAuthorship W1977290961A5027769343 @default.
• W1977290961 hasAuthorship W1977290961A5028794135 @default.
• W1977290961 hasAuthorship W1977290961A5031727021 @default.
• W1977290961 hasAuthorship W1977290961A5052184745 @default.
• W1977290961 hasAuthorship W1977290961A5060603552 @default.
• W1977290961 hasAuthorship W1977290961A5062391734 @default.
• W1977290961 hasAuthorship W1977290961A5077265846 @default.
• W1977290961 hasAuthorship W1977290961A5077796292 @default.
• W1977290961 hasAuthorship W1977290961A5081682571 @default.
• W1977290961 hasAuthorship W1977290961A5082530337 @default.
• W1977290961 hasBestOaLocation W19772909612 @default.
• W1977290961 hasConcept C106289968 @default.
• W1977290961 hasConcept C113196181 @default.
• W1977290961 hasConcept C15213710 @default.
• W1977290961 hasConcept C162356407 @default.
• W1977290961 hasConcept C175467004 @default.
• W1977290961 hasConcept C185592680 @default.
• W1977290961 hasConcept C31827203 @default.

• next