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- W1977312521 abstract "To study severe infectious complications in a cohort of patients with systemic lupus erythematosus (SLE).Retrospective study of 705 patients followed from January 1980 to January 2008. Data are expressed in percentages.The frequency of severe infectious was 38.6%. The etiology was bacterial 54.4%, viric 30.4% and opportunist in 15.2% patients. Involved organs were: Lung 38.2%, kidney 48.9%, central nervous system 43%. 43.75% patients received pulsed ciclofosfamide therapy and 88.6% received glucocorticoids (39.7% pulsed). The mortality was 27.7%.At present, infection is an important cause of mortality in patients with SLE. Early diagnosis of infectious complications is very important in SLE." @default.
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- W1977312521 date "2010-09-01" @default.
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- W1977312521 title "Infecciones graves en una cohorte de pacientes con lupus eritematoso sistémico" @default.
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- W1977312521 doi "https://doi.org/10.1016/j.medcli.2010.03.026" @default.
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