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- W1977330306 abstract "The vasculature, an organ that penetrates every other organ, is ideally poised to be the site where pools of stem cells are placed, to be deployed and committed in response to feedback regulation, and to respond to demands for new vascular structures. These pools of multipotent cells are often under the regulation of various members of the transforming growth factor‐β superfamily, including the bone morphogenetic proteins and their antagonists. Regulation of stem cell populations affects their recruitment, differentiation, spatial organization, and their coordination with host tissue. Loss and dysregulation of feedback control cause a variety of diseases that involve ectopic tissue formation, including atherosclerotic lesion formation and calcification, diabetic vasculopathies, and arteriovenous malformations. Disclosure of potential conflicts of interest is found at the end of this article." @default.
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- W1977330306 date "2012-02-14" @default.
- W1977330306 modified "2023-09-27" @default.
- W1977330306 title "Concise Review: Applying Stem Cell Biology to Vascular Structures" @default.
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- W1977330306 doi "https://doi.org/10.1002/stem.1027" @default.
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