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- W1977348170 abstract "In the study of the inhibition of enzyme reactions the Michaelis–Menten model is extended to include two experimental variables and three or more parameters. We combine the three-parameter models for competitive and non competitive inhibition in a four-parameter model and use optimum design theory to find D- and Ds-optimum designs for discriminating between the models. These designs are compared with compound T-optimum designs which provide the most powerful tests for discrimination between models. A single design is found with high discrimination efficiency whichever model is true." @default.
- W1977348170 created "2016-06-24" @default.
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- W1977348170 date "2012-07-01" @default.
- W1977348170 modified "2023-09-27" @default.
- W1977348170 title "Optimum Experimental Designs for Choosing Between Competitive and Non Competitive Models of Enzyme Inhibition" @default.
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- W1977348170 doi "https://doi.org/10.1080/03610926.2011.593720" @default.
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