FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977401965> ?p ?o ?g. }

• W1977401965 endingPage "208" @default.
• W1977401965 startingPage "201" @default.
• W1977401965 abstract "The frequency of sister-chromatid exchange (SCE) was studied in cultures of human lymphocytes exposed to vinyl acetate (VA) or acetaldehyde (AA) for various time periods and in different phases of the cell cycle. Equimolar concentrations (0.1-2.4 mM) of VA and AA were found to induce very similar, dose-dependent increases of SCE. The SCE frequency in cells treated with VA was found to increase linearly with exposure times up to 24 h. Cells exposed to VA or AA in the late G1-phase of the cell cycle showed a 2-fold higher SCE frequency than cells exposed in early G1. Cultures treated with VA in the first G1-phase showed a significant increase of SCE during 3 subsequent cell cycles. These results indicate that (1) AA is likely to be responsible for the SCE induction observed in VA-treated cells, (2) the SCE-inducing activity of AA persists for several cell cycles in vitro, and (3) removal of SCE-inducing AA-damage occurs during G1. Taken together, the data suggest that AA has a slow turn-over in human lymphocytes in vitro, and may accumulate in the cells, possibly by forming reversible Schiff bases, and when released gives rise to SCE-inducing DNA cross-links." @default.
• W1977401965 created "2016-06-24" @default.
• W1977401965 creator A5059113813 @default.
• W1977401965 creator A5083535247 @default.
• W1977401965 date "1985-12-01" @default.
• W1977401965 modified "2023-09-27" @default.
• W1977401965 title "Induction and persistence of SCE-inducing damage in human lymphocytes exposed to vinyl acetate and acetaldehyde in vitro" @default.
• W1977401965 cites W1966236690 @default.
• W1977401965 cites W1970899404 @default.
• W1977401965 cites W1976917904 @default.
• W1977401965 cites W2015439829 @default.
• W1977401965 cites W2018367004 @default.
• W1977401965 cites W2027973534 @default.
• W1977401965 cites W2028958186 @default.
• W1977401965 cites W2043158304 @default.
• W1977401965 cites W2044969577 @default.
• W1977401965 cites W2053012139 @default.
• W1977401965 cites W2078150483 @default.
• W1977401965 cites W2080081438 @default.
• W1977401965 cites W2092145977 @default.
• W1977401965 cites W2118386638 @default.
• W1977401965 doi "https://doi.org/10.1016/0165-1218(85)90086-2" @default.
• W1977401965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4079951" @default.
• W1977401965 hasPublicationYear "1985" @default.
• W1977401965 type Work @default.
• W1977401965 sameAs 1977401965 @default.
• W1977401965 citedByCount "55" @default.
• W1977401965 countsByYear W19774019652012 @default.
• W1977401965 countsByYear W19774019652013 @default.
• W1977401965 countsByYear W19774019652015 @default.
• W1977401965 countsByYear W19774019652021 @default.
• W1977401965 crossrefType "journal-article" @default.
• W1977401965 hasAuthorship W1977401965A5059113813 @default.
• W1977401965 hasAuthorship W1977401965A5083535247 @default.
• W1977401965 hasConcept C104317684 @default.
• W1977401965 hasConcept C143425029 @default.
• W1977401965 hasConcept C1491633281 @default.
• W1977401965 hasConcept C153911025 @default.
• W1977401965 hasConcept C15920480 @default.
• W1977401965 hasConcept C178790620 @default.
• W1977401965 hasConcept C185592680 @default.
• W1977401965 hasConcept C202751555 @default.
• W1977401965 hasConcept C203014093 @default.
• W1977401965 hasConcept C2776093513 @default.
• W1977401965 hasConcept C2777595113 @default.
• W1977401965 hasConcept C2777761686 @default.
• W1977401965 hasConcept C2779071816 @default.
• W1977401965 hasConcept C2780161600 @default.
• W1977401965 hasConcept C29537977 @default.
• W1977401965 hasConcept C30481170 @default.
• W1977401965 hasConcept C521977710 @default.
• W1977401965 hasConcept C54355233 @default.
• W1977401965 hasConcept C552990157 @default.
• W1977401965 hasConcept C55493867 @default.
• W1977401965 hasConcept C81885089 @default.
• W1977401965 hasConcept C8502773 @default.
• W1977401965 hasConcept C86803240 @default.
• W1977401965 hasConceptScore W1977401965C104317684 @default.
• W1977401965 hasConceptScore W1977401965C143425029 @default.
• W1977401965 hasConceptScore W1977401965C1491633281 @default.
• W1977401965 hasConceptScore W1977401965C153911025 @default.
• W1977401965 hasConceptScore W1977401965C15920480 @default.
• W1977401965 hasConceptScore W1977401965C178790620 @default.
• W1977401965 hasConceptScore W1977401965C185592680 @default.
• W1977401965 hasConceptScore W1977401965C202751555 @default.
• W1977401965 hasConceptScore W1977401965C203014093 @default.
• W1977401965 hasConceptScore W1977401965C2776093513 @default.
• W1977401965 hasConceptScore W1977401965C2777595113 @default.
• W1977401965 hasConceptScore W1977401965C2777761686 @default.
• W1977401965 hasConceptScore W1977401965C2779071816 @default.
• W1977401965 hasConceptScore W1977401965C2780161600 @default.
• W1977401965 hasConceptScore W1977401965C29537977 @default.
• W1977401965 hasConceptScore W1977401965C30481170 @default.
• W1977401965 hasConceptScore W1977401965C521977710 @default.
• W1977401965 hasConceptScore W1977401965C54355233 @default.
• W1977401965 hasConceptScore W1977401965C552990157 @default.
• W1977401965 hasConceptScore W1977401965C55493867 @default.
• W1977401965 hasConceptScore W1977401965C81885089 @default.
• W1977401965 hasConceptScore W1977401965C8502773 @default.
• W1977401965 hasConceptScore W1977401965C86803240 @default.
• W1977401965 hasIssue "3" @default.
• W1977401965 hasLocation W19774019651 @default.
• W1977401965 hasLocation W19774019652 @default.
• W1977401965 hasOpenAccess W1977401965 @default.
• W1977401965 hasPrimaryLocation W19774019651 @default.
• W1977401965 hasRelatedWork W1966870632 @default.
• W1977401965 hasRelatedWork W1977401965 @default.
• W1977401965 hasRelatedWork W1978091080 @default.
• W1977401965 hasRelatedWork W2049679162 @default.
• W1977401965 hasRelatedWork W2053161363 @default.
• W1977401965 hasRelatedWork W2073911086 @default.
• W1977401965 hasRelatedWork W2077299293 @default.
• W1977401965 hasRelatedWork W3157756799 @default.
• W1977401965 hasRelatedWork W4253958865 @default.
• W1977401965 hasRelatedWork W53786239 @default.
• W1977401965 hasVolume "158" @default.
• W1977401965 isParatext "false" @default.
• W1977401965 isRetracted "false" @default.

• next