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- W1977408097 abstract "The heterogeneity of acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS) has led to a multiplicity of treatments, from cytotoxic agents to signal transduction modulators, cell-cycle inhibitors and epigenetic therapies. While some have shown promising initial results, the outlook for AML patients, particularly older and relapsed patients, as well as patients whose cells exhibit certain adverse chromosomal abnormalities or mutant oncoproteins, continues to be grim. Combination chemotherapy using new agents that act at a number of different levels may provide the greatest potential for successful future therapies. A select number of new agents, approaches and combinations are reviewed here." @default.
- W1977408097 created "2016-06-24" @default.
- W1977408097 creator A5061036144 @default.
- W1977408097 date "2009-12-01" @default.
- W1977408097 modified "2023-09-24" @default.
- W1977408097 title "New agents for AML and MDS" @default.
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- W1977408097 doi "https://doi.org/10.1016/j.beha.2009.08.003" @default.
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