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- W1977482955 abstract "The 5-year survival rate of marginally resectable nonsmall cell lung cancer (NSCLC) patients treated by platinum/gemcitabine induction chemotherapy and surgery is not well documented. We studied 47 consecutive patients with NSCLC stage IIIA-IIIB (non-N3) treated with platinum/gemcitabine induction chemotherapy (median: 3 cycles) and evaluated the objective response, resectability, surgical morbidity/mortality and long-term survival rate. The induction chemotherapy was completed by 45/47 patients. Objective response was: 36% partial, 32% stable disease, 28% progression, 0% complete; two patients (4%) died during induction chemotherapy. tumor respectability was 74%, postoperative morbidity 34%, mortality nil. 26% of patients were unresectable. In the whole cohort the 5-year survival was 25% (95%CI, 17%-32%) and the median survival was 22 months (28 months in resected patients; 7 months in unresectable).In conclusion, in the intention-to-treat population undergoing platinum/gemcitabine induction chemotherapy, resectability was high (74%) and the 5-year survival rate was 25%. median survival in resected cases was three-fold greater than in the unresected." @default.
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- W1977482955 date "2010-06-01" @default.
- W1977482955 modified "2023-09-27" @default.
- W1977482955 title "Five-Year Survival of Stage IIIA-IIIB (Non-N3) Non-Small Cell Lung Cancer Patients after Platinum/Gemcitabine Induction Chemotherapy and Surgery" @default.
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- W1977482955 doi "https://doi.org/10.1179/joc.2010.22.3.191" @default.
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