Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977599140> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1977599140 abstract "Abstract The effects of microsomal enzyme inducers on hepatic function in mice and rats were studied when these drugs were given before or after chemical poisoning. If gastric administration of phetharbital (50–75 mg/kg/day) was begun 12–18 hr after CCl 4 (1.4–1.8 ml/kg) was given, the 20 min sulfobromophthalein (BSP) retention returned to normal in 3–4 days, while animals not receiving the inducer still had markedly abnormal values. SGPT values, which rose after CCl 4 , were not affected by phetharbital. The rise in BSP retention after white phosphorus (2–7.5 mg/kg) also returned to normal more rapidly if daily phetharbital followed the administration of the poison. After phosphorus, SGPT did not rise and phetharbital had no effect on the activity of this enzyme. Phenobarbital had the same effect as phetharbital on BSP retention if given after phosphorus, but 3,4-benzpyrene, oxyphenbutazone or cyclizine did not share this effect. No inducer affected mortality or weight gain after phosphorus poisoning of mice. Phenobarbital pretreatment increased mortality after CCl 4 but not after phosphorus." @default.
- W1977599140 created "2016-06-24" @default.
- W1977599140 creator A5066954652 @default.
- W1977599140 date "1972-07-01" @default.
- W1977599140 modified "2023-09-25" @default.
- W1977599140 title "Effects of microsomal enzyme inducers on animals poisoned with hepatotoxins" @default.
- W1977599140 cites W1973633830 @default.
- W1977599140 cites W1976449722 @default.
- W1977599140 cites W1981292392 @default.
- W1977599140 cites W2012652819 @default.
- W1977599140 cites W2017208557 @default.
- W1977599140 cites W2078668637 @default.
- W1977599140 cites W2079458953 @default.
- W1977599140 cites W2089915260 @default.
- W1977599140 cites W2263023695 @default.
- W1977599140 cites W3023211482 @default.
- W1977599140 cites W71716523 @default.
- W1977599140 doi "https://doi.org/10.1016/0041-008x(72)90239-6" @default.
- W1977599140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5041367" @default.
- W1977599140 hasPublicationYear "1972" @default.
- W1977599140 type Work @default.
- W1977599140 sameAs 1977599140 @default.
- W1977599140 citedByCount "9" @default.
- W1977599140 crossrefType "journal-article" @default.
- W1977599140 hasAuthorship W1977599140A5066954652 @default.
- W1977599140 hasConcept C104317684 @default.
- W1977599140 hasConcept C126322002 @default.
- W1977599140 hasConcept C132154277 @default.
- W1977599140 hasConcept C134018914 @default.
- W1977599140 hasConcept C149971331 @default.
- W1977599140 hasConcept C178790620 @default.
- W1977599140 hasConcept C181199279 @default.
- W1977599140 hasConcept C185592680 @default.
- W1977599140 hasConcept C2225953 @default.
- W1977599140 hasConcept C2778793413 @default.
- W1977599140 hasConcept C2910856874 @default.
- W1977599140 hasConcept C29730261 @default.
- W1977599140 hasConcept C510538283 @default.
- W1977599140 hasConcept C512861765 @default.
- W1977599140 hasConcept C55493867 @default.
- W1977599140 hasConcept C71924100 @default.
- W1977599140 hasConcept C87644729 @default.
- W1977599140 hasConcept C98274493 @default.
- W1977599140 hasConceptScore W1977599140C104317684 @default.
- W1977599140 hasConceptScore W1977599140C126322002 @default.
- W1977599140 hasConceptScore W1977599140C132154277 @default.
- W1977599140 hasConceptScore W1977599140C134018914 @default.
- W1977599140 hasConceptScore W1977599140C149971331 @default.
- W1977599140 hasConceptScore W1977599140C178790620 @default.
- W1977599140 hasConceptScore W1977599140C181199279 @default.
- W1977599140 hasConceptScore W1977599140C185592680 @default.
- W1977599140 hasConceptScore W1977599140C2225953 @default.
- W1977599140 hasConceptScore W1977599140C2778793413 @default.
- W1977599140 hasConceptScore W1977599140C2910856874 @default.
- W1977599140 hasConceptScore W1977599140C29730261 @default.
- W1977599140 hasConceptScore W1977599140C510538283 @default.
- W1977599140 hasConceptScore W1977599140C512861765 @default.
- W1977599140 hasConceptScore W1977599140C55493867 @default.
- W1977599140 hasConceptScore W1977599140C71924100 @default.
- W1977599140 hasConceptScore W1977599140C87644729 @default.
- W1977599140 hasConceptScore W1977599140C98274493 @default.
- W1977599140 hasLocation W19775991401 @default.
- W1977599140 hasLocation W19775991402 @default.
- W1977599140 hasOpenAccess W1977599140 @default.
- W1977599140 hasPrimaryLocation W19775991401 @default.
- W1977599140 hasRelatedWork W1968359841 @default.
- W1977599140 hasRelatedWork W1993728684 @default.
- W1977599140 hasRelatedWork W1997473965 @default.
- W1977599140 hasRelatedWork W2005191555 @default.
- W1977599140 hasRelatedWork W2016170192 @default.
- W1977599140 hasRelatedWork W2038675936 @default.
- W1977599140 hasRelatedWork W2050840353 @default.
- W1977599140 hasRelatedWork W2111589725 @default.
- W1977599140 hasRelatedWork W2413189091 @default.
- W1977599140 hasRelatedWork W2988909632 @default.
- W1977599140 isParatext "false" @default.
- W1977599140 isRetracted "false" @default.
- W1977599140 magId "1977599140" @default.
- W1977599140 workType "article" @default.