Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977612476> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1977612476 endingPage "621" @default.
- W1977612476 startingPage "618" @default.
- W1977612476 abstract "Glucocorticoids are effective drugs for the treatment of allergic skin diseases. In the present study, we observed the effects of prednisolone on the cutaneous reaction and skin barrier function in mice treated with a hapten, 2,4-dinitrofluorobenzene. Repeated hapten application onto the mouse ear resulted in a potent ear swelling with an elevation of specific serum IgE. The ear swelling appeared following the second application of the hapten and peaked at 24 h after each application. Specific serum IgE was detected first after the fourth hapten application. Topical treatment with prednisolone apparently suppressed the swelling, whereas it failed to affect the serum specific IgE level. The hapten application caused an increase in transepidermal water loss, which was potently inhibited by prednisolone, although the water content was not affected. Amounts of triglyceride and cholesterol in the ear skin increased after repeated hapten applications, whereas the relative amount of free fatty acid and ceramide diminished. Prednisolone exhibited an inhibitory effect on the changes in lipid content. Thus prednisolone apparently inhibits the alteration of skin barrier function caused by hapten application as well as the cutaneous reaction." @default.
- W1977612476 created "2016-06-24" @default.
- W1977612476 creator A5051109631 @default.
- W1977612476 creator A5058262430 @default.
- W1977612476 creator A5075638989 @default.
- W1977612476 creator A5077189198 @default.
- W1977612476 date "2003-01-01" @default.
- W1977612476 modified "2023-10-03" @default.
- W1977612476 title "Effects of Prednisolone on the Cutaneous Reaction and Skin Barrier Function in Mice Treated with a Hapten" @default.
- W1977612476 cites W1894741156 @default.
- W1977612476 cites W1980120225 @default.
- W1977612476 cites W1980525161 @default.
- W1977612476 cites W1994723670 @default.
- W1977612476 cites W2000512232 @default.
- W1977612476 cites W2033921570 @default.
- W1977612476 cites W2034476237 @default.
- W1977612476 cites W2045960810 @default.
- W1977612476 cites W2063914080 @default.
- W1977612476 cites W2067017343 @default.
- W1977612476 cites W2086001407 @default.
- W1977612476 cites W2090456980 @default.
- W1977612476 cites W2143863285 @default.
- W1977612476 cites W2154966672 @default.
- W1977612476 cites W2169484065 @default.
- W1977612476 cites W65284930 @default.
- W1977612476 doi "https://doi.org/10.1248/bpb.26.618" @default.
- W1977612476 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12736500" @default.
- W1977612476 hasPublicationYear "2003" @default.
- W1977612476 type Work @default.
- W1977612476 sameAs 1977612476 @default.
- W1977612476 citedByCount "11" @default.
- W1977612476 countsByYear W19776124762018 @default.
- W1977612476 countsByYear W19776124762019 @default.
- W1977612476 countsByYear W19776124762021 @default.
- W1977612476 crossrefType "journal-article" @default.
- W1977612476 hasAuthorship W1977612476A5051109631 @default.
- W1977612476 hasAuthorship W1977612476A5058262430 @default.
- W1977612476 hasAuthorship W1977612476A5075638989 @default.
- W1977612476 hasAuthorship W1977612476A5077189198 @default.
- W1977612476 hasBestOaLocation W19776124761 @default.
- W1977612476 hasConcept C126322002 @default.
- W1977612476 hasConcept C134018914 @default.
- W1977612476 hasConcept C141105273 @default.
- W1977612476 hasConcept C142724271 @default.
- W1977612476 hasConcept C159654299 @default.
- W1977612476 hasConcept C185592680 @default.
- W1977612476 hasConcept C203014093 @default.
- W1977612476 hasConcept C2776715498 @default.
- W1977612476 hasConcept C2778370115 @default.
- W1977612476 hasConcept C29144244 @default.
- W1977612476 hasConcept C71924100 @default.
- W1977612476 hasConcept C95150158 @default.
- W1977612476 hasConcept C98274493 @default.
- W1977612476 hasConceptScore W1977612476C126322002 @default.
- W1977612476 hasConceptScore W1977612476C134018914 @default.
- W1977612476 hasConceptScore W1977612476C141105273 @default.
- W1977612476 hasConceptScore W1977612476C142724271 @default.
- W1977612476 hasConceptScore W1977612476C159654299 @default.
- W1977612476 hasConceptScore W1977612476C185592680 @default.
- W1977612476 hasConceptScore W1977612476C203014093 @default.
- W1977612476 hasConceptScore W1977612476C2776715498 @default.
- W1977612476 hasConceptScore W1977612476C2778370115 @default.
- W1977612476 hasConceptScore W1977612476C29144244 @default.
- W1977612476 hasConceptScore W1977612476C71924100 @default.
- W1977612476 hasConceptScore W1977612476C95150158 @default.
- W1977612476 hasConceptScore W1977612476C98274493 @default.
- W1977612476 hasIssue "5" @default.
- W1977612476 hasLocation W19776124761 @default.
- W1977612476 hasLocation W19776124762 @default.
- W1977612476 hasOpenAccess W1977612476 @default.
- W1977612476 hasPrimaryLocation W19776124761 @default.
- W1977612476 hasRelatedWork W1971984977 @default.
- W1977612476 hasRelatedWork W1977612476 @default.
- W1977612476 hasRelatedWork W1998779640 @default.
- W1977612476 hasRelatedWork W2001250928 @default.
- W1977612476 hasRelatedWork W2017226993 @default.
- W1977612476 hasRelatedWork W2037737262 @default.
- W1977612476 hasRelatedWork W2065811422 @default.
- W1977612476 hasRelatedWork W2106441560 @default.
- W1977612476 hasRelatedWork W2134223583 @default.
- W1977612476 hasRelatedWork W2899084033 @default.
- W1977612476 hasVolume "26" @default.
- W1977612476 isParatext "false" @default.
- W1977612476 isRetracted "false" @default.
- W1977612476 magId "1977612476" @default.
- W1977612476 workType "article" @default.