Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977640534> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W1977640534 endingPage "431" @default.
- W1977640534 startingPage "425" @default.
- W1977640534 abstract "Abstract. There are two basic antigenic components in Cryptobia that are responsible for the anaemia in infected rainbow trout. A ‘lytic component’, which is dosage-dependent, causes lysis of red blood cells independent of antibody or complement. The second, an ‘immune-complex-forming component’, attaches to red blood cells, forms immune complexes with specific antibody and activates complement resulting in haemolysis. These two antigenic components, from both live and lysed Cryptobia, were present in the serum of infected fish. When sonicated antigen or heat-inactivated antiserum (from infected fish) was incubated with red cells from uninfected fish, a portion of the red cells was lysed and a positive Coombs’ reaction was observed with the remaining intact red cells. The positive Coombs’ reaction was due to immune complexes adsorbed onto the red cells and these lysed when incubated with complement. Antibody by itself did not adsorb onto the red cells. From the fourth week post-infection, a positive Coombs’ reaction was observed in all infected fish and haemolysis occurred with complement. The authors suggest that, in infected fish, one or more components of the complement cascade is depleted continually during infection and that the anaemia is due to the lytic action of the antigen and immune complex formation on red cells. These lead to intra-vascular haemolysis as well as erythrophagocytosis. In general, the mechanism of anaemia in cryptobiosis appears similar to that in African trypanosomiasis." @default.
- W1977640534 created "2016-06-24" @default.
- W1977640534 creator A5050573452 @default.
- W1977640534 creator A5065485979 @default.
- W1977640534 date "1988-09-01" @default.
- W1977640534 modified "2023-10-16" @default.
- W1977640534 title "Cryptobia salmositica: an in vitro and in vivo study on the mechanism of anaemia in infected rainbow trout, Salmo gairdneri Richardson" @default.
- W1977640534 cites W1966781128 @default.
- W1977640534 cites W1977742201 @default.
- W1977640534 cites W1978780497 @default.
- W1977640534 cites W2007881383 @default.
- W1977640534 cites W2009755219 @default.
- W1977640534 cites W2033754297 @default.
- W1977640534 cites W2115025799 @default.
- W1977640534 cites W2127426588 @default.
- W1977640534 cites W2138942321 @default.
- W1977640534 cites W2419041782 @default.
- W1977640534 cites W52922811 @default.
- W1977640534 doi "https://doi.org/10.1111/j.1365-2761.1988.tb00738.x" @default.
- W1977640534 hasPublicationYear "1988" @default.
- W1977640534 type Work @default.
- W1977640534 sameAs 1977640534 @default.
- W1977640534 citedByCount "32" @default.
- W1977640534 countsByYear W19776405342014 @default.
- W1977640534 countsByYear W19776405342022 @default.
- W1977640534 crossrefType "journal-article" @default.
- W1977640534 hasAuthorship W1977640534A5050573452 @default.
- W1977640534 hasAuthorship W1977640534A5065485979 @default.
- W1977640534 hasConcept C111684460 @default.
- W1977640534 hasConcept C147483822 @default.
- W1977640534 hasConcept C159047783 @default.
- W1977640534 hasConcept C159654299 @default.
- W1977640534 hasConcept C203014093 @default.
- W1977640534 hasConcept C2776966407 @default.
- W1977640534 hasConcept C2910801743 @default.
- W1977640534 hasConcept C55493867 @default.
- W1977640534 hasConcept C57409179 @default.
- W1977640534 hasConcept C86803240 @default.
- W1977640534 hasConcept C8891405 @default.
- W1977640534 hasConcept C89423630 @default.
- W1977640534 hasConceptScore W1977640534C111684460 @default.
- W1977640534 hasConceptScore W1977640534C147483822 @default.
- W1977640534 hasConceptScore W1977640534C159047783 @default.
- W1977640534 hasConceptScore W1977640534C159654299 @default.
- W1977640534 hasConceptScore W1977640534C203014093 @default.
- W1977640534 hasConceptScore W1977640534C2776966407 @default.
- W1977640534 hasConceptScore W1977640534C2910801743 @default.
- W1977640534 hasConceptScore W1977640534C55493867 @default.
- W1977640534 hasConceptScore W1977640534C57409179 @default.
- W1977640534 hasConceptScore W1977640534C86803240 @default.
- W1977640534 hasConceptScore W1977640534C8891405 @default.
- W1977640534 hasConceptScore W1977640534C89423630 @default.
- W1977640534 hasIssue "5" @default.
- W1977640534 hasLocation W19776405341 @default.
- W1977640534 hasOpenAccess W1977640534 @default.
- W1977640534 hasPrimaryLocation W19776405341 @default.
- W1977640534 hasRelatedWork W13594097 @default.
- W1977640534 hasRelatedWork W1484759019 @default.
- W1977640534 hasRelatedWork W1565112821 @default.
- W1977640534 hasRelatedWork W2030921111 @default.
- W1977640534 hasRelatedWork W2040191638 @default.
- W1977640534 hasRelatedWork W2059286235 @default.
- W1977640534 hasRelatedWork W2220102944 @default.
- W1977640534 hasRelatedWork W2405988911 @default.
- W1977640534 hasRelatedWork W2409441623 @default.
- W1977640534 hasRelatedWork W4210976760 @default.
- W1977640534 hasVolume "11" @default.
- W1977640534 isParatext "false" @default.
- W1977640534 isRetracted "false" @default.
- W1977640534 magId "1977640534" @default.
- W1977640534 workType "article" @default.