FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977692174> ?p ?o ?g. }

• W1977692174 endingPage "604" @default.
• W1977692174 startingPage "604" @default.
• W1977692174 abstract "With the rapid growth in the availability of genome sequence data, the automated identification of orthologous genes between species (orthologs) is of fundamental importance to facilitate functional annotation and studies on comparative and evolutionary genomics. Genes with no apparent orthologs between the bovine and human genome may be responsible for major differences between the species, however, such genes are often neglected in functional genomics studies.A BLAST-based method was exploited to explore the current annotation and orthology predictions in Ensembl. Genes with no orthologs between the two genomes were classified into groups based on alignments, ontology, manual curation and publicly available information. Starting from a high quality and specific set of orthology predictions, as provided by Ensembl, hidden relationship between genes and genomes of different mammalian species were unveiled using a highly sensitive approach, based on sequence similarity and genomic comparison.The analysis identified 3,801 bovine genes with no orthologs in human and 1010 human genes with no orthologs in cow, among which 411 and 43 genes, respectively, had no match at all in the other species. Most of the apparently non-orthologous genes may potentially have orthologs which were missed in the annotation process, despite having a high percentage of identity, because of differences in gene length and structure. The comparative analysis reported here identified gene variants, new genes and species-specific features and gave an overview of the other side of orthology which may help to improve the annotation of the bovine genome and the knowledge of structural differences between species." @default.
• W1977692174 created "2016-06-24" @default.
• W1977692174 creator A5044650094 @default.
• W1977692174 creator A5046326452 @default.
• W1977692174 creator A5048139885 @default.
• W1977692174 creator A5054641536 @default.
• W1977692174 creator A5071430674 @default.
• W1977692174 date "2009-01-01" @default.
• W1977692174 modified "2023-10-10" @default.
• W1977692174 title "The other side of comparative genomics: genes with no orthologs between the cow and other mammalian species" @default.
• W1977692174 cites W1537213512 @default.
• W1977692174 cites W1542595575 @default.
• W1977692174 cites W1709622954 @default.
• W1977692174 cites W1958476169 @default.
• W1977692174 cites W1972007609 @default.
• W1977692174 cites W1972017488 @default.
• W1977692174 cites W1973780314 @default.
• W1977692174 cites W1974383394 @default.
• W1977692174 cites W1977027195 @default.
• W1977692174 cites W1988905498 @default.
• W1977692174 cites W1997113958 @default.
• W1977692174 cites W2007046901 @default.
• W1977692174 cites W2007447692 @default.
• W1977692174 cites W2008856488 @default.
• W1977692174 cites W2037883697 @default.
• W1977692174 cites W2045534443 @default.
• W1977692174 cites W2069516109 @default.
• W1977692174 cites W2080153599 @default.
• W1977692174 cites W2085161553 @default.
• W1977692174 cites W2096525273 @default.
• W1977692174 cites W2096939566 @default.
• W1977692174 cites W2100668314 @default.
• W1977692174 cites W2103017472 @default.
• W1977692174 cites W2106013076 @default.
• W1977692174 cites W2106044656 @default.
• W1977692174 cites W2112884978 @default.
• W1977692174 cites W2114611642 @default.
• W1977692174 cites W2118930999 @default.
• W1977692174 cites W2124166542 @default.
• W1977692174 cites W2124908487 @default.
• W1977692174 cites W2128643990 @default.
• W1977692174 cites W2132023322 @default.
• W1977692174 cites W2137084536 @default.
• W1977692174 cites W2137464714 @default.
• W1977692174 cites W2138578706 @default.
• W1977692174 cites W2142237411 @default.
• W1977692174 cites W2143335572 @default.
• W1977692174 cites W2145100181 @default.
• W1977692174 cites W2146453000 @default.
• W1977692174 cites W2150934173 @default.
• W1977692174 cites W2151464048 @default.
• W1977692174 cites W2154044807 @default.
• W1977692174 cites W2154380613 @default.
• W1977692174 cites W2155606054 @default.
• W1977692174 cites W2158714788 @default.
• W1977692174 cites W2161062388 @default.
• W1977692174 cites W2162742404 @default.
• W1977692174 cites W2166187656 @default.
• W1977692174 cites W2167188257 @default.
• W1977692174 cites W2169748335 @default.
• W1977692174 cites W2169929748 @default.
• W1977692174 cites W2592555944 @default.
• W1977692174 cites W2441941171 @default.
• W1977692174 doi "https://doi.org/10.1186/1471-2164-10-604" @default.
• W1977692174 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2808326" @default.
• W1977692174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20003425" @default.
• W1977692174 hasPublicationYear "2009" @default.
• W1977692174 type Work @default.
• W1977692174 sameAs 1977692174 @default.
• W1977692174 citedByCount "9" @default.
• W1977692174 countsByYear W19776921742013 @default.
• W1977692174 countsByYear W19776921742015 @default.
• W1977692174 countsByYear W19776921742016 @default.
• W1977692174 countsByYear W19776921742020 @default.
• W1977692174 countsByYear W19776921742021 @default.
• W1977692174 countsByYear W19776921742022 @default.
• W1977692174 countsByYear W19776921742023 @default.
• W1977692174 crossrefType "journal-article" @default.
• W1977692174 hasAuthorship W1977692174A5044650094 @default.
• W1977692174 hasAuthorship W1977692174A5046326452 @default.
• W1977692174 hasAuthorship W1977692174A5048139885 @default.
• W1977692174 hasAuthorship W1977692174A5054641536 @default.
• W1977692174 hasAuthorship W1977692174A5071430674 @default.
• W1977692174 hasBestOaLocation W19776921741 @default.
• W1977692174 hasConcept C104317684 @default.
• W1977692174 hasConcept C105176652 @default.
• W1977692174 hasConcept C105565629 @default.
• W1977692174 hasConcept C141231307 @default.
• W1977692174 hasConcept C141674004 @default.
• W1977692174 hasConcept C161078062 @default.
• W1977692174 hasConcept C189206191 @default.
• W1977692174 hasConcept C197077220 @default.
• W1977692174 hasConcept C2776321320 @default.
• W1977692174 hasConcept C2776473694 @default.
• W1977692174 hasConcept C2908923196 @default.
• W1977692174 hasConcept C2909108991 @default.
• W1977692174 hasConcept C54355233 @default.
• W1977692174 hasConcept C70721500 @default.

• next