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- W1977696560 abstract "Protein Hal is a human γ4 heavy-chain disease protein whose molecular weight is reduced from 55,000 to 25,000 in 6 M guanidine due to the lack of disulfide bonds between heavy chains. Studies of aminoacid sequence indicate that it contains a gap of about 240 residues, starting 10 residues from the N-terminal end and including the rest of the Fd fragment, as well as the hinge region. Normal sequence apparently resumes at a methionine residue (position 252) in the second constant domain (C H 2) and seems normal from there to the carboxyl end of the molecule. These results imply that reinitiation of translation at an internal AUG codon occurs in protein Hal." @default.
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- W1977696560 date "1973-04-01" @default.
- W1977696560 modified "2023-10-01" @default.
- W1977696560 title "Protein Hal: Partial Deletion of a “γ” Immunoglobulin Gene(s) and Apparent Reinitiation at an Internal AUG Codon" @default.
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- W1977696560 doi "https://doi.org/10.1073/pnas.70.4.1073" @default.
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