Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977707073> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1977707073 endingPage "303" @default.
- W1977707073 startingPage "298" @default.
- W1977707073 abstract "<i>Background/Aims:</i> Risk of ischaemic stroke (IS) was associated with total homocysteine (tHCY). On the other hand, serum selenium (Se) exhibited anti-aging and cardiopreventive effects. Se and tHCY showed relationships in animals but these were contradictory or inconclusive in humans; therefore, we searched for such associations in acute IS. <i>Methods:</i> Ninety-four participants aged around 47 years were identified and 39 patients versus 46 healthy controls were analysed. Clinical, laboratory (blinded) and risk factor questionnaire methods were used. Comparison, correlation and multifactorial regression analyses were applied. <i>Results:</i> IS patients were similar to controls concerning age and gender. IS was prevalent in the carotid system (76.9%); 82.1% had a subacute onset. IS patients expressed higher tHCY (14.65 ± 9.79 µmol/l) and lower Se levels (1.3 ± 0.5 µmol/l). Twice as many IS patients (23%) had optimal Se levels of <1.01 µmol/l. Subjects with hyperhomocysteinaemia (tHCY ≧15 µmol/l) showed lower Se levels during IS; Se accounted for 15.4% of tHCY variations (R = –0.393; p = 0.015) with unit change increasing tHCY by 8.25 units. Se remained predictive of tHCY levels after adjustments (vitamin B<sub>6</sub>, fibrinogen, triglycerides). <i>Conclusions:</i> Lower Se was observed during acute IS, being inversely associated with and predicting increased tHCY levels. Of note, there were more IS patients with suboptimal Se than controls." @default.
- W1977707073 created "2016-06-24" @default.
- W1977707073 creator A5043773062 @default.
- W1977707073 creator A5047150313 @default.
- W1977707073 creator A5061410786 @default.
- W1977707073 creator A5090808267 @default.
- W1977707073 date "2008-01-01" @default.
- W1977707073 modified "2023-09-23" @default.
- W1977707073 title "Associations between Serum Selenium and Total Plasma Homocysteine during the Acute Phase of Ischaemic Stroke" @default.
- W1977707073 cites W1830735030 @default.
- W1977707073 cites W1950422130 @default.
- W1977707073 cites W2006178210 @default.
- W1977707073 cites W2011805985 @default.
- W1977707073 cites W2027214846 @default.
- W1977707073 cites W2027809599 @default.
- W1977707073 cites W2044042359 @default.
- W1977707073 cites W2088275971 @default.
- W1977707073 cites W2113333920 @default.
- W1977707073 cites W2114372071 @default.
- W1977707073 cites W2142061140 @default.
- W1977707073 cites W2146206984 @default.
- W1977707073 cites W2154350322 @default.
- W1977707073 cites W2187590530 @default.
- W1977707073 cites W2261417749 @default.
- W1977707073 cites W2401201111 @default.
- W1977707073 cites W2408803965 @default.
- W1977707073 cites W2608791844 @default.
- W1977707073 doi "https://doi.org/10.1159/000157884" @default.
- W1977707073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18824858" @default.
- W1977707073 hasPublicationYear "2008" @default.
- W1977707073 type Work @default.
- W1977707073 sameAs 1977707073 @default.
- W1977707073 citedByCount "20" @default.
- W1977707073 countsByYear W19777070732015 @default.
- W1977707073 countsByYear W19777070732017 @default.
- W1977707073 countsByYear W19777070732018 @default.
- W1977707073 countsByYear W19777070732020 @default.
- W1977707073 countsByYear W19777070732021 @default.
- W1977707073 countsByYear W19777070732022 @default.
- W1977707073 countsByYear W19777070732023 @default.
- W1977707073 crossrefType "journal-article" @default.
- W1977707073 hasAuthorship W1977707073A5043773062 @default.
- W1977707073 hasAuthorship W1977707073A5047150313 @default.
- W1977707073 hasAuthorship W1977707073A5061410786 @default.
- W1977707073 hasAuthorship W1977707073A5090808267 @default.
- W1977707073 hasConcept C126322002 @default.
- W1977707073 hasConcept C127413603 @default.
- W1977707073 hasConcept C134018914 @default.
- W1977707073 hasConcept C178790620 @default.
- W1977707073 hasConcept C185592680 @default.
- W1977707073 hasConcept C2777090595 @default.
- W1977707073 hasConcept C2779036427 @default.
- W1977707073 hasConcept C2780645631 @default.
- W1977707073 hasConcept C50440223 @default.
- W1977707073 hasConcept C553756173 @default.
- W1977707073 hasConcept C71924100 @default.
- W1977707073 hasConcept C78519656 @default.
- W1977707073 hasConcept C90924648 @default.
- W1977707073 hasConceptScore W1977707073C126322002 @default.
- W1977707073 hasConceptScore W1977707073C127413603 @default.
- W1977707073 hasConceptScore W1977707073C134018914 @default.
- W1977707073 hasConceptScore W1977707073C178790620 @default.
- W1977707073 hasConceptScore W1977707073C185592680 @default.
- W1977707073 hasConceptScore W1977707073C2777090595 @default.
- W1977707073 hasConceptScore W1977707073C2779036427 @default.
- W1977707073 hasConceptScore W1977707073C2780645631 @default.
- W1977707073 hasConceptScore W1977707073C50440223 @default.
- W1977707073 hasConceptScore W1977707073C553756173 @default.
- W1977707073 hasConceptScore W1977707073C71924100 @default.
- W1977707073 hasConceptScore W1977707073C78519656 @default.
- W1977707073 hasConceptScore W1977707073C90924648 @default.
- W1977707073 hasIssue "6" @default.
- W1977707073 hasLocation W19777070731 @default.
- W1977707073 hasLocation W19777070732 @default.
- W1977707073 hasOpenAccess W1977707073 @default.
- W1977707073 hasPrimaryLocation W19777070731 @default.
- W1977707073 hasRelatedWork W1974207972 @default.
- W1977707073 hasRelatedWork W2034242699 @default.
- W1977707073 hasRelatedWork W2072921720 @default.
- W1977707073 hasRelatedWork W2076785284 @default.
- W1977707073 hasRelatedWork W2087722477 @default.
- W1977707073 hasRelatedWork W2090665682 @default.
- W1977707073 hasRelatedWork W2129793021 @default.
- W1977707073 hasRelatedWork W2140328987 @default.
- W1977707073 hasRelatedWork W2265884416 @default.
- W1977707073 hasRelatedWork W2413973859 @default.
- W1977707073 hasVolume "60" @default.
- W1977707073 isParatext "false" @default.
- W1977707073 isRetracted "false" @default.
- W1977707073 magId "1977707073" @default.
- W1977707073 workType "article" @default.