Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977734089> ?p ?o ?g. }
- W1977734089 endingPage "1423" @default.
- W1977734089 startingPage "1419" @default.
- W1977734089 abstract "Baclofen (10 and 20 mg/kg, i.p.) induced catatonia in rats within 10 min of its administration and the effect lasted for 3 hr. Muscimol (100 ng i.c.v. or 1 mg/kg, i.p.) as well as GABA (5 micrograms i.c.v.) potentiated the effect without producing any effect per se. Bicuculline, bromocriptine and scopolamine failed to modify the catatonia induced by baclofen, thereby ruling out the involvement of GABAA receptors, dopaminergic and cholinergic mechanisms. However, GABAB receptor antagonists, such as homotaurine and delta-amino-n-valeric acid, reversed the catatonia induced by baclofen in rats. Since baclofen is known to bind to a subpopulation of GABA receptors (bicuculline-insensitive) and baclofen-induced catatonia was susceptible to reversal by homotaurine and delta-amino-n-valeric acid, it is suggested that this effect could be mediated through GABAB receptors." @default.
- W1977734089 created "2016-06-24" @default.
- W1977734089 creator A5010469690 @default.
- W1977734089 creator A5045323788 @default.
- W1977734089 date "1987-09-01" @default.
- W1977734089 modified "2023-10-17" @default.
- W1977734089 title "Baclofen induces catatonia in rats" @default.
- W1977734089 cites W107947039 @default.
- W1977734089 cites W1968498254 @default.
- W1977734089 cites W1972522095 @default.
- W1977734089 cites W1984959935 @default.
- W1977734089 cites W1987663265 @default.
- W1977734089 cites W1993143141 @default.
- W1977734089 cites W1993333230 @default.
- W1977734089 cites W1994383216 @default.
- W1977734089 cites W1994993913 @default.
- W1977734089 cites W2001191203 @default.
- W1977734089 cites W2012458599 @default.
- W1977734089 cites W2021491106 @default.
- W1977734089 cites W2022351042 @default.
- W1977734089 cites W2022798120 @default.
- W1977734089 cites W2032535087 @default.
- W1977734089 cites W2032985342 @default.
- W1977734089 cites W2050737030 @default.
- W1977734089 cites W2058336745 @default.
- W1977734089 cites W2066628109 @default.
- W1977734089 cites W2066883358 @default.
- W1977734089 cites W2066904533 @default.
- W1977734089 cites W2070020128 @default.
- W1977734089 cites W2070551515 @default.
- W1977734089 cites W2071161962 @default.
- W1977734089 cites W2071832184 @default.
- W1977734089 cites W2074752011 @default.
- W1977734089 cites W2093204280 @default.
- W1977734089 cites W2095581818 @default.
- W1977734089 cites W2136959259 @default.
- W1977734089 cites W2169767365 @default.
- W1977734089 cites W2415907929 @default.
- W1977734089 cites W333788534 @default.
- W1977734089 doi "https://doi.org/10.1016/0028-3908(87)90108-0" @default.
- W1977734089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2823166" @default.
- W1977734089 hasPublicationYear "1987" @default.
- W1977734089 type Work @default.
- W1977734089 sameAs 1977734089 @default.
- W1977734089 citedByCount "21" @default.
- W1977734089 countsByYear W19777340892015 @default.
- W1977734089 countsByYear W19777340892022 @default.
- W1977734089 crossrefType "journal-article" @default.
- W1977734089 hasAuthorship W1977734089A5010469690 @default.
- W1977734089 hasAuthorship W1977734089A5045323788 @default.
- W1977734089 hasConcept C101027131 @default.
- W1977734089 hasConcept C118552586 @default.
- W1977734089 hasConcept C126322002 @default.
- W1977734089 hasConcept C134018914 @default.
- W1977734089 hasConcept C137183658 @default.
- W1977734089 hasConcept C168258287 @default.
- W1977734089 hasConcept C170493617 @default.
- W1977734089 hasConcept C185592680 @default.
- W1977734089 hasConcept C2776412080 @default.
- W1977734089 hasConcept C2776856834 @default.
- W1977734089 hasConcept C2778938600 @default.
- W1977734089 hasConcept C2778941822 @default.
- W1977734089 hasConcept C2779064019 @default.
- W1977734089 hasConcept C2779188335 @default.
- W1977734089 hasConcept C2780763569 @default.
- W1977734089 hasConcept C2781201050 @default.
- W1977734089 hasConcept C513476851 @default.
- W1977734089 hasConcept C55493867 @default.
- W1977734089 hasConcept C71315377 @default.
- W1977734089 hasConcept C71924100 @default.
- W1977734089 hasConcept C79636183 @default.
- W1977734089 hasConcept C98274493 @default.
- W1977734089 hasConceptScore W1977734089C101027131 @default.
- W1977734089 hasConceptScore W1977734089C118552586 @default.
- W1977734089 hasConceptScore W1977734089C126322002 @default.
- W1977734089 hasConceptScore W1977734089C134018914 @default.
- W1977734089 hasConceptScore W1977734089C137183658 @default.
- W1977734089 hasConceptScore W1977734089C168258287 @default.
- W1977734089 hasConceptScore W1977734089C170493617 @default.
- W1977734089 hasConceptScore W1977734089C185592680 @default.
- W1977734089 hasConceptScore W1977734089C2776412080 @default.
- W1977734089 hasConceptScore W1977734089C2776856834 @default.
- W1977734089 hasConceptScore W1977734089C2778938600 @default.
- W1977734089 hasConceptScore W1977734089C2778941822 @default.
- W1977734089 hasConceptScore W1977734089C2779064019 @default.
- W1977734089 hasConceptScore W1977734089C2779188335 @default.
- W1977734089 hasConceptScore W1977734089C2780763569 @default.
- W1977734089 hasConceptScore W1977734089C2781201050 @default.
- W1977734089 hasConceptScore W1977734089C513476851 @default.
- W1977734089 hasConceptScore W1977734089C55493867 @default.
- W1977734089 hasConceptScore W1977734089C71315377 @default.
- W1977734089 hasConceptScore W1977734089C71924100 @default.
- W1977734089 hasConceptScore W1977734089C79636183 @default.
- W1977734089 hasConceptScore W1977734089C98274493 @default.
- W1977734089 hasIssue "9" @default.
- W1977734089 hasLocation W19777340891 @default.
- W1977734089 hasLocation W19777340892 @default.
- W1977734089 hasOpenAccess W1977734089 @default.