FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977802851> ?p ?o ?g. }

• W1977802851 endingPage "321" @default.
• W1977802851 startingPage "316" @default.
• W1977802851 abstract "A hydrophilic ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM]BF4) was successfully employed as co-solvent for asymmetric bioreduction of ethyl acetoacetate (EOB) to ethyl (R)-3-hydroxybutyrate (R-EHB) catalyzed by Pichia membranaefaciens Hansen ZJPH07 cells. The results demonstrated that the addition of [BMIM]BF4 in reaction system can markedly reduce the substrate inhibition and moderately improve the enantioselectivity compared to that in monophasic aqueous system. Among different alcohols and carbohydrates tried as co-substrate, glucose was a proper electron donor. Although isopropanol gave the best enantioselectivity with the highest yield, S-enantiomer was obtained. To optimize the bioreduction, some reaction parameters for the biosynthesis of R-EHB in this IL-containing system were investigated, such as temperature, buffer pH, shaking speed, substrate concentration, wet cells concentration and reaction time. Under the optimum conditions, best conversion of 77.8% and product enantiomeric excess (e.e.) of 73.0% were obtained. A comparative study was performed either in the presence or in the absence of [BMIM]BF4, higher reaction yield (77.8% versus 68.5%) and product e.e. (73.0% versus 65.1%) were observed in IL-containing system with 0.55 M of the substrate, but 0.35 M of substrate concentration for the reduction in aqueous system without the addition of [BMIM]BF4." @default.
• W1977802851 created "2016-06-24" @default.
• W1977802851 creator A5031636736 @default.
• W1977802851 creator A5049339754 @default.
• W1977802851 creator A5050034119 @default.
• W1977802851 creator A5051240875 @default.
• W1977802851 date "2009-03-01" @default.
• W1977802851 modified "2023-09-27" @default.
• W1977802851 title "Microbial reduction of ethyl acetoacetate to ethyl (R)-3-hydroxybutyrate in an ionic liquid containing system" @default.
• W1977802851 cites W1968964240 @default.
• W1977802851 cites W1977654491 @default.
• W1977802851 cites W1986149872 @default.
• W1977802851 cites W1996215310 @default.
• W1977802851 cites W1999773325 @default.
• W1977802851 cites W2000730391 @default.
• W1977802851 cites W2001501144 @default.
• W1977802851 cites W2016531491 @default.
• W1977802851 cites W2019601138 @default.
• W1977802851 cites W2022917256 @default.
• W1977802851 cites W2038481390 @default.
• W1977802851 cites W2038530768 @default.
• W1977802851 cites W2040225377 @default.
• W1977802851 cites W2043030933 @default.
• W1977802851 cites W2044233481 @default.
• W1977802851 cites W2052304862 @default.
• W1977802851 cites W2053370697 @default.
• W1977802851 cites W2059631245 @default.
• W1977802851 cites W2075950651 @default.
• W1977802851 cites W2076579425 @default.
• W1977802851 cites W2078094561 @default.
• W1977802851 cites W2079025217 @default.
• W1977802851 cites W2079803741 @default.
• W1977802851 cites W2080677711 @default.
• W1977802851 cites W2093827064 @default.
• W1977802851 cites W2111985609 @default.
• W1977802851 cites W2161503513 @default.
• W1977802851 cites W2166291477 @default.
• W1977802851 cites W2950591954 @default.
• W1977802851 cites W2950961588 @default.
• W1977802851 cites W4241320206 @default.
• W1977802851 cites W4248104288 @default.
• W1977802851 doi "https://doi.org/10.1016/j.procbio.2008.11.007" @default.
• W1977802851 hasPublicationYear "2009" @default.
• W1977802851 type Work @default.
• W1977802851 sameAs 1977802851 @default.
• W1977802851 citedByCount "41" @default.
• W1977802851 countsByYear W19778028512012 @default.
• W1977802851 countsByYear W19778028512013 @default.
• W1977802851 countsByYear W19778028512014 @default.
• W1977802851 countsByYear W19778028512015 @default.
• W1977802851 countsByYear W19778028512016 @default.
• W1977802851 countsByYear W19778028512018 @default.
• W1977802851 countsByYear W19778028512019 @default.
• W1977802851 countsByYear W19778028512021 @default.
• W1977802851 crossrefType "journal-article" @default.
• W1977802851 hasAuthorship W1977802851A5031636736 @default.
• W1977802851 hasAuthorship W1977802851A5049339754 @default.
• W1977802851 hasAuthorship W1977802851A5050034119 @default.
• W1977802851 hasAuthorship W1977802851A5051240875 @default.
• W1977802851 hasConcept C111368507 @default.
• W1977802851 hasConcept C127313418 @default.
• W1977802851 hasConcept C134121241 @default.
• W1977802851 hasConcept C13965031 @default.
• W1977802851 hasConcept C146686406 @default.
• W1977802851 hasConcept C154881586 @default.
• W1977802851 hasConcept C161790260 @default.
• W1977802851 hasConcept C178790620 @default.
• W1977802851 hasConcept C184651966 @default.
• W1977802851 hasConcept C185592680 @default.
• W1977802851 hasConcept C191503008 @default.
• W1977802851 hasConcept C191897082 @default.
• W1977802851 hasConcept C192562407 @default.
• W1977802851 hasConcept C2776308844 @default.
• W1977802851 hasConcept C2777289219 @default.
• W1977802851 hasConcept C2780471494 @default.
• W1977802851 hasConcept C2780872544 @default.
• W1977802851 hasConcept C3141732 @default.
• W1977802851 hasConceptScore W1977802851C111368507 @default.
• W1977802851 hasConceptScore W1977802851C127313418 @default.
• W1977802851 hasConceptScore W1977802851C134121241 @default.
• W1977802851 hasConceptScore W1977802851C13965031 @default.
• W1977802851 hasConceptScore W1977802851C146686406 @default.
• W1977802851 hasConceptScore W1977802851C154881586 @default.
• W1977802851 hasConceptScore W1977802851C161790260 @default.
• W1977802851 hasConceptScore W1977802851C178790620 @default.
• W1977802851 hasConceptScore W1977802851C184651966 @default.
• W1977802851 hasConceptScore W1977802851C185592680 @default.
• W1977802851 hasConceptScore W1977802851C191503008 @default.
• W1977802851 hasConceptScore W1977802851C191897082 @default.
• W1977802851 hasConceptScore W1977802851C192562407 @default.
• W1977802851 hasConceptScore W1977802851C2776308844 @default.
• W1977802851 hasConceptScore W1977802851C2777289219 @default.
• W1977802851 hasConceptScore W1977802851C2780471494 @default.
• W1977802851 hasConceptScore W1977802851C2780872544 @default.
• W1977802851 hasConceptScore W1977802851C3141732 @default.
• W1977802851 hasIssue "3" @default.
• W1977802851 hasLocation W19778028511 @default.
• W1977802851 hasOpenAccess W1977802851 @default.

• next