FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977824948> ?p ?o ?g. }

• W1977824948 endingPage "33" @default.
• W1977824948 startingPage "19" @default.
• W1977824948 abstract "Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease, a murine model for multiple sclerosis, involves recruitment of T cells and macrophages to the CNS after infection. We hypothesized that CCR2, the only known receptor for CCL2, would be required for TMEV-induced demyelinating disease development because of its role in macrophage recruitment. TMEV-infected SJL CCR2 knockout (KO) mice showed decreased long-term clinical disease severity and less demyelination compared with controls. Flow cytometric data indicated that macrophages (CD45(high) CD11b(+) ) in the CNS of TMEV-infected CCR2 KO mice were decreased compared with control mice throughout disease. CD4(+) and CD8(+) T cell percentages in the CNS of TMEV-infected control and CCR2 KO mice were similar over the course of disease. There were no apparent differences between CCR2 KO and control peripheral immune responses. The frequency of interferon-gamma-producing T cells in response to proteolipid protein 139-151 in the CNS was also similar during the autoimmunity stage of TMEV-induced demyelinating disease. These data suggest that CCR2 is important for development of clinical disease by regulating macrophage accumulation after TMEV infection." @default.
• W1977824948 created "2016-06-24" @default.
• W1977824948 creator A5016036240 @default.
• W1977824948 creator A5033876610 @default.
• W1977824948 creator A5048874942 @default.
• W1977824948 creator A5055939902 @default.
• W1977824948 creator A5069703075 @default.
• W1977824948 creator A5084633857 @default.
• W1977824948 date "2007-03-01" @default.
• W1977824948 modified "2023-10-16" @default.
• W1977824948 title "CCR2 Regulates Development of Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease" @default.
• W1977824948 cites W1632273139 @default.
• W1977824948 cites W1822012598 @default.
• W1977824948 cites W1887755235 @default.
• W1977824948 cites W1980444303 @default.
• W1977824948 cites W1991183685 @default.
• W1977824948 cites W2001894281 @default.
• W1977824948 cites W2009295096 @default.
• W1977824948 cites W2038911566 @default.
• W1977824948 cites W2040275555 @default.
• W1977824948 cites W2043465498 @default.
• W1977824948 cites W2045834436 @default.
• W1977824948 cites W2074051982 @default.
• W1977824948 cites W2080932190 @default.
• W1977824948 cites W2081193695 @default.
• W1977824948 cites W2084854552 @default.
• W1977824948 cites W2091988171 @default.
• W1977824948 cites W2093864910 @default.
• W1977824948 cites W2098635583 @default.
• W1977824948 cites W2102628016 @default.
• W1977824948 cites W2106895889 @default.
• W1977824948 cites W2111718223 @default.
• W1977824948 cites W2127980776 @default.
• W1977824948 cites W2128287837 @default.
• W1977824948 cites W2133793569 @default.
• W1977824948 cites W2134587746 @default.
• W1977824948 cites W2138780833 @default.
• W1977824948 cites W2142540702 @default.
• W1977824948 cites W2142792546 @default.
• W1977824948 cites W2144052344 @default.
• W1977824948 cites W2144604423 @default.
• W1977824948 cites W2145397502 @default.
• W1977824948 cites W2151363901 @default.
• W1977824948 cites W2152318693 @default.
• W1977824948 cites W2153956608 @default.
• W1977824948 cites W2156906544 @default.
• W1977824948 cites W2158552513 @default.
• W1977824948 cites W2161530562 @default.
• W1977824948 cites W2163804088 @default.
• W1977824948 cites W2165101346 @default.
• W1977824948 cites W2165299403 @default.
• W1977824948 cites W2330517410 @default.
• W1977824948 cites W97158386 @default.
• W1977824948 doi "https://doi.org/10.1089/vim.2006.0068" @default.
• W1977824948 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17425418" @default.
• W1977824948 hasPublicationYear "2007" @default.
• W1977824948 type Work @default.
• W1977824948 sameAs 1977824948 @default.
• W1977824948 citedByCount "27" @default.
• W1977824948 countsByYear W19778249482012 @default.
• W1977824948 countsByYear W19778249482013 @default.
• W1977824948 countsByYear W19778249482014 @default.
• W1977824948 countsByYear W19778249482016 @default.
• W1977824948 countsByYear W19778249482017 @default.
• W1977824948 countsByYear W19778249482018 @default.
• W1977824948 countsByYear W19778249482021 @default.
• W1977824948 countsByYear W19778249482022 @default.
• W1977824948 crossrefType "journal-article" @default.
• W1977824948 hasAuthorship W1977824948A5016036240 @default.
• W1977824948 hasAuthorship W1977824948A5033876610 @default.
• W1977824948 hasAuthorship W1977824948A5048874942 @default.
• W1977824948 hasAuthorship W1977824948A5055939902 @default.
• W1977824948 hasAuthorship W1977824948A5069703075 @default.
• W1977824948 hasAuthorship W1977824948A5084633857 @default.
• W1977824948 hasConcept C12823836 @default.
• W1977824948 hasConcept C13373296 @default.
• W1977824948 hasConcept C142724271 @default.
• W1977824948 hasConcept C203014093 @default.
• W1977824948 hasConcept C206615009 @default.
• W1977824948 hasConcept C2777899865 @default.
• W1977824948 hasConcept C2778486448 @default.
• W1977824948 hasConcept C2778531937 @default.
• W1977824948 hasConcept C2779134260 @default.
• W1977824948 hasConcept C2780640218 @default.
• W1977824948 hasConcept C71924100 @default.
• W1977824948 hasConcept C86803240 @default.
• W1977824948 hasConcept C8891405 @default.
• W1977824948 hasConceptScore W1977824948C12823836 @default.
• W1977824948 hasConceptScore W1977824948C13373296 @default.
• W1977824948 hasConceptScore W1977824948C142724271 @default.
• W1977824948 hasConceptScore W1977824948C203014093 @default.
• W1977824948 hasConceptScore W1977824948C206615009 @default.
• W1977824948 hasConceptScore W1977824948C2777899865 @default.
• W1977824948 hasConceptScore W1977824948C2778486448 @default.
• W1977824948 hasConceptScore W1977824948C2778531937 @default.
• W1977824948 hasConceptScore W1977824948C2779134260 @default.
• W1977824948 hasConceptScore W1977824948C2780640218 @default.
• W1977824948 hasConceptScore W1977824948C71924100 @default.

• next