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• W1977832827 abstract "Vibrations of a homopolymer DNA with localized hydrogen bond defects have been examined using the recently developed decaying mode theory for long-chain polymers with local structural defects. For a poly(dA)-poly(dT) homopolymer having perturbed hydrogen bonds in one base pair, a localized mode at 63.2 cm-1 has been found. This mode has a very nearly pure H-bond stretch or breathing character, although the backbones do not separate. This agrees in frequency with a similar result found by other authors using a different approach. We search the full microwave frequency range for other local modes for several models of weakened H bonds. Besides the local mode with breathing characteristics, local modes with other characteristic motions were found, but only for asymmetrically perturbed bonds. We find in general that local modes are not very robust, requiring quite specific, narrow ranges in parameter space. They are also not abundant, there being only three in our most prolific model." @default.
• W1977832827 created "2016-06-24" @default.
• W1977832827 creator A5021015741 @default.
• W1977832827 creator A5060707764 @default.
• W1977832827 date "1994-12-01" @default.
• W1977832827 modified "2023-09-28" @default.
• W1977832827 title "Local modes in a DNA polymer with hydrogen bond defect" @default.
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• W1977832827 doi "https://doi.org/10.1016/s0006-3495(94)80731-3" @default.
• W1977832827 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1225629" @default.
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