Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977906909> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1977906909 endingPage "779" @default.
- W1977906909 startingPage "774" @default.
- W1977906909 abstract "Patients with acute liver failure have a disturbed amino acid metabolism and a compromised oxidative metabolism in the brain. A limited number of clinically neuroprotective interventions are available. This study aimed at assessing the effect of fractionated plasma separation and adsorption (FPSA), an extracorporeal liver support system, on cerebral amino acids and lactate to pyruvate ratio.Seven patients with acute liver failure and high risk of intracranial hypertension were included for cerebral microdialysis and intracranial pressure monitoring. Microdialysate, arterial blood, and venous blood from the jugular bulb were sampled, before and after an FPSA session, and the content of nineteen amino acids, lactate, and pyruvate was determined.The total amino acid concentration in arterial plasma was not significantly reduced by FPSA (11.2 mM (3.0-26.0 mM) vs. 9.7 mM (2.7-13.6 mM); median with range). The total amino acid content in the microdialysate was 5.6 mM both before and after FPSA and no change in glutamine content was observed in plasma or microdialysate. The content of aromatic amino acids in arterial plasma, but not in microdialysate, was marginally reduced (p<0.05). Arterial lactate concentration and lactate to pyruvate ratio in the microdialysate did not change following FPSA.One single treatment session with FPSA had a marginal effect on plasma amino acid composition. We found minimal changes in the amino acids content in the microdialysate, and the lactate to pyruvate ratio was unaffected." @default.
- W1977906909 created "2016-06-24" @default.
- W1977906909 creator A5001915986 @default.
- W1977906909 creator A5022504541 @default.
- W1977906909 creator A5042963646 @default.
- W1977906909 creator A5075535143 @default.
- W1977906909 creator A5078474678 @default.
- W1977906909 creator A5081856911 @default.
- W1977906909 date "2012-10-01" @default.
- W1977906909 modified "2023-09-26" @default.
- W1977906909 title "The effect of fractionated plasma separation and adsorption on cerebral amino acid metabolism and oxidative metabolism during acute liver failure" @default.
- W1977906909 cites W1963710631 @default.
- W1977906909 cites W1986030016 @default.
- W1977906909 cites W1996583528 @default.
- W1977906909 cites W1997865837 @default.
- W1977906909 cites W2010220557 @default.
- W1977906909 cites W2014863292 @default.
- W1977906909 cites W2015771906 @default.
- W1977906909 cites W2026102094 @default.
- W1977906909 cites W2036761886 @default.
- W1977906909 cites W2039636675 @default.
- W1977906909 cites W2067735566 @default.
- W1977906909 cites W2069979635 @default.
- W1977906909 cites W2072631125 @default.
- W1977906909 cites W2087148853 @default.
- W1977906909 cites W2087245233 @default.
- W1977906909 cites W2105894386 @default.
- W1977906909 cites W2118603239 @default.
- W1977906909 cites W2167507703 @default.
- W1977906909 cites W4211193493 @default.
- W1977906909 cites W2096388104 @default.
- W1977906909 doi "https://doi.org/10.1016/j.jhep.2012.06.004" @default.
- W1977906909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22691571" @default.
- W1977906909 hasPublicationYear "2012" @default.
- W1977906909 type Work @default.
- W1977906909 sameAs 1977906909 @default.
- W1977906909 citedByCount "10" @default.
- W1977906909 countsByYear W19779069092012 @default.
- W1977906909 countsByYear W19779069092013 @default.
- W1977906909 countsByYear W19779069092015 @default.
- W1977906909 countsByYear W19779069092018 @default.
- W1977906909 countsByYear W19779069092019 @default.
- W1977906909 countsByYear W19779069092021 @default.
- W1977906909 countsByYear W19779069092023 @default.
- W1977906909 crossrefType "journal-article" @default.
- W1977906909 hasAuthorship W1977906909A5001915986 @default.
- W1977906909 hasAuthorship W1977906909A5022504541 @default.
- W1977906909 hasAuthorship W1977906909A5042963646 @default.
- W1977906909 hasAuthorship W1977906909A5075535143 @default.
- W1977906909 hasAuthorship W1977906909A5078474678 @default.
- W1977906909 hasAuthorship W1977906909A5081856911 @default.
- W1977906909 hasConcept C126322002 @default.
- W1977906909 hasConcept C134018914 @default.
- W1977906909 hasConcept C185592680 @default.
- W1977906909 hasConcept C2779349466 @default.
- W1977906909 hasConcept C28406088 @default.
- W1977906909 hasConcept C50156730 @default.
- W1977906909 hasConcept C515207424 @default.
- W1977906909 hasConcept C55493867 @default.
- W1977906909 hasConcept C62231903 @default.
- W1977906909 hasConcept C71924100 @default.
- W1977906909 hasConceptScore W1977906909C126322002 @default.
- W1977906909 hasConceptScore W1977906909C134018914 @default.
- W1977906909 hasConceptScore W1977906909C185592680 @default.
- W1977906909 hasConceptScore W1977906909C2779349466 @default.
- W1977906909 hasConceptScore W1977906909C28406088 @default.
- W1977906909 hasConceptScore W1977906909C50156730 @default.
- W1977906909 hasConceptScore W1977906909C515207424 @default.
- W1977906909 hasConceptScore W1977906909C55493867 @default.
- W1977906909 hasConceptScore W1977906909C62231903 @default.
- W1977906909 hasConceptScore W1977906909C71924100 @default.
- W1977906909 hasIssue "4" @default.
- W1977906909 hasLocation W19779069091 @default.
- W1977906909 hasLocation W19779069092 @default.
- W1977906909 hasOpenAccess W1977906909 @default.
- W1977906909 hasPrimaryLocation W19779069091 @default.
- W1977906909 hasRelatedWork W1927591950 @default.
- W1977906909 hasRelatedWork W1969640580 @default.
- W1977906909 hasRelatedWork W2023660858 @default.
- W1977906909 hasRelatedWork W2079421120 @default.
- W1977906909 hasRelatedWork W2080613476 @default.
- W1977906909 hasRelatedWork W2139232831 @default.
- W1977906909 hasRelatedWork W2153965615 @default.
- W1977906909 hasRelatedWork W2329349150 @default.
- W1977906909 hasRelatedWork W2413474627 @default.
- W1977906909 hasRelatedWork W2748952813 @default.
- W1977906909 hasVolume "57" @default.
- W1977906909 isParatext "false" @default.
- W1977906909 isRetracted "false" @default.
- W1977906909 magId "1977906909" @default.
- W1977906909 workType "article" @default.