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- W1977969920 abstract "ABSTRACT Gonadotropin‐releasing hormone (GnRH) is a key molecule in the control of reproduction in mammals. It is generally thought that the secretion of GnRH into the pituitary portal vessels is governed by two distinct neural mechanisms: the pulsatile and surge mode centers. The former is called the GnRH pulse generator, and this neural substrate plays a role as the master regulator of the reproductive function. An electrophysiological technique for monitoring the neural activity of the GnRH pulse generator has been established in the Shiba goat. The central actions of several neuropeptides have been assessed using this system. Results suggest that several neuropeptides including neuropeptide Y, cholecystokinin‐octapeptide and melanocortins are involved in the regulation of the GnRH pulse generator activity in the goat. Each input of those neuropeptides likely represents a unique mechanism conveying specific information about changes in the internal and external environments such as olfactory signals, nutrition, stress, and steroidal milieu, to the GnRH pulse generator. Further elucidations of actions of neurotransmitters on the GnRH pulse generator may serve for better understanding of the neuroendocrine control of reproduction in the ruminant." @default.
- W1977969920 created "2016-06-24" @default.
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- W1977969920 date "2007-03-07" @default.
- W1977969920 modified "2023-10-11" @default.
- W1977969920 title "Neuroendocrine control of reproductive function in ruminants" @default.
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- W1977969920 doi "https://doi.org/10.1111/j.1740-0929.2007.00413.x" @default.
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