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- W1977995866 abstract "To the Editor:— Dr. Harry Seneca has written an article entitled Long-Acting Sulfonamides in Urinary Tract Infections ( 198 :975, 1966). I do not disagree with the content insofar as the sulfonamides are concerned. On page 979, Dr. Seneca states that nitrofurantoin does not give rise to biologically active tissue levels; yet the work we and others have published clearly demonstrates the presence of significant renal interstitial (renal lymph) concentrations of nitrofurantion. 1-3 In fact, these interstitial concentrations exceed the corresponding blood levels. Our published data also clearly show that the renal lymph concentrations of nitrofurantoin are biologically active and suppress growth of Escherichia coli . Sweeping statements such as Dr. Seneca's run the danger of ignoring recent advances, leaving the reader with an erroneous conclusion." @default.
- W1977995866 created "2016-06-24" @default.
- W1977995866 creator A5088354027 @default.
- W1977995866 date "1967-05-29" @default.
- W1977995866 modified "2023-09-26" @default.
- W1977995866 title "Long-Acting Sulfonamides In Urinary Tract Infection" @default.
- W1977995866 cites W1988058494 @default.
- W1977995866 doi "https://doi.org/10.1001/jama.1967.03120220101034" @default.
- W1977995866 hasPublicationYear "1967" @default.
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