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- W1978032370 abstract "The influence of the pharmacokinetics of drug-carrier conjugates and free drug and the pharmacodynamics of therapeutic and toxic response on the potential for success of a drug-targeting system have been considered. Using previous investigations and the present discussion it is possible to make some qualified statements about optimisation of drug targeting. These statements are dependent on the extent of understanding of the disease process, the anatomy and pathophysiology of the target site, the pharmacokinetics of drug carrier and free drug, the mechanism of drug release and the pharmacodynamics of therapeutic and toxic effects." @default.
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- W1978032370 date "1989-03-01" @default.
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- W1978032370 title "Pharmacokinetic and pharmacodynamic aspects of site-specific drug delivery" @default.
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- W1978032370 doi "https://doi.org/10.1016/0169-409x(89)90008-2" @default.
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