FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978040069> ?p ?o ?g. }

• W1978040069 endingPage "322" @default.
• W1978040069 startingPage "315" @default.
• W1978040069 abstract "purpose: The long-term effects of transjugular intrahepatic portosystemic shunts on renal sodium excretion are not known. We sought to determine these long-term effects, as well as to measure the effects of a sodium load in patients who are free of ascites. subjects and methods: Ten patients with cirrhosis who had been successfully treated with transjugular intrahepatic portosystemic stent shunt for refractory ascites were studied before the shunt and again at 6 and 14 months after the shunt while on a 22 mmol sodium/day diet. At 14 months they were also studied on a 200 mmol sodium/day diet for 7 days without diuretics. Renal sodium handling, central blood volume, neurohumoral factors, and hepatic function were measured. results: Sodium balance was negative at 6 months (urinary sodium excretion [mean ± SD] 51 ± 11 mmol/day versus 7 ± 2 mmol/day pre-shunt; P <0.05), was maintained at 14 months (22 ± 4 mmol/day; P <0.05 versus pre-shunt), and was associated with normalization of renin activity and aldosterone levels, but not norepinephrine levels, as well as significantly improved renal hemodynamic measurements. Sodium loading with 200 mmol/day resulted in weight gain associated with increased central blood volume and appropriate renal sodium handling in most but not all patients (urinary sodium excretion 188 ± 14 mmol/day), despite persistent nonsuppressibility of sympathetic hyperactivity. conclusions: In cirrhotic patients with refractory ascites treated with a transjugular intrahepatic portosystemic stent shunt, long-term renal sodium handling is improved. Adequate intravascular filling in ascites-free cirrhotic patients with normal portal pressure permits an improved but not normalized renal response to a sodium load, possibly due to persistently elevated sympathetic activity. Therefore, these patients should increase their sodium intake cautiously." @default.
• W1978040069 created "2016-06-24" @default.
• W1978040069 creator A5016693256 @default.
• W1978040069 creator A5029712431 @default.
• W1978040069 creator A5036097898 @default.
• W1978040069 creator A5049172310 @default.
• W1978040069 date "1999-03-01" @default.
• W1978040069 modified "2023-10-16" @default.
• W1978040069 title "Long-term renal sodium handling in patients with cirrhosis treated with transjugular intrahepatic portosystemic shunts for refractory ascites22Part of this work was performed while holding a Fellowship in Hepatology from Schering Canada." @default.
• W1978040069 cites W1916614783 @default.
• W1978040069 cites W1974393761 @default.
• W1978040069 cites W1976692217 @default.
• W1978040069 cites W1989172382 @default.
• W1978040069 cites W1990084655 @default.
• W1978040069 cites W2023406623 @default.
• W1978040069 cites W2024382278 @default.
• W1978040069 cites W2036408424 @default.
• W1978040069 cites W2054641887 @default.
• W1978040069 cites W2060123467 @default.
• W1978040069 cites W2070070452 @default.
• W1978040069 cites W2073331975 @default.
• W1978040069 cites W2088740988 @default.
• W1978040069 cites W2089285373 @default.
• W1978040069 cites W2090747764 @default.
• W1978040069 cites W2115436231 @default.
• W1978040069 cites W2117688067 @default.
• W1978040069 cites W2126357414 @default.
• W1978040069 cites W2130191989 @default.
• W1978040069 cites W2170424959 @default.
• W1978040069 cites W2318484454 @default.
• W1978040069 cites W4298331656 @default.
• W1978040069 cites W4300133716 @default.
• W1978040069 doi "https://doi.org/10.1016/s0002-9343(99)00029-7" @default.
• W1978040069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10190381" @default.
• W1978040069 hasPublicationYear "1999" @default.
• W1978040069 type Work @default.
• W1978040069 sameAs 1978040069 @default.
• W1978040069 citedByCount "51" @default.
• W1978040069 countsByYear W19780400692012 @default.
• W1978040069 countsByYear W19780400692013 @default.
• W1978040069 countsByYear W19780400692014 @default.
• W1978040069 countsByYear W19780400692015 @default.
• W1978040069 countsByYear W19780400692016 @default.
• W1978040069 countsByYear W19780400692017 @default.
• W1978040069 countsByYear W19780400692018 @default.
• W1978040069 countsByYear W19780400692019 @default.
• W1978040069 countsByYear W19780400692020 @default.
• W1978040069 countsByYear W19780400692022 @default.
• W1978040069 countsByYear W19780400692023 @default.
• W1978040069 crossrefType "journal-article" @default.
• W1978040069 hasAuthorship W1978040069A5016693256 @default.
• W1978040069 hasAuthorship W1978040069A5029712431 @default.
• W1978040069 hasAuthorship W1978040069A5036097898 @default.
• W1978040069 hasAuthorship W1978040069A5049172310 @default.
• W1978040069 hasConcept C126322002 @default.
• W1978040069 hasConcept C126894567 @default.
• W1978040069 hasConcept C134018914 @default.
• W1978040069 hasConcept C159641895 @default.
• W1978040069 hasConcept C178790620 @default.
• W1978040069 hasConcept C185592680 @default.
• W1978040069 hasConcept C2777214474 @default.
• W1978040069 hasConcept C2777720800 @default.
• W1978040069 hasConcept C2778674827 @default.
• W1978040069 hasConcept C2778808290 @default.
• W1978040069 hasConcept C2780325230 @default.
• W1978040069 hasConcept C2780496750 @default.
• W1978040069 hasConcept C2781033279 @default.
• W1978040069 hasConcept C537181965 @default.
• W1978040069 hasConcept C56900294 @default.
• W1978040069 hasConcept C71924100 @default.
• W1978040069 hasConcept C90924648 @default.
• W1978040069 hasConceptScore W1978040069C126322002 @default.
• W1978040069 hasConceptScore W1978040069C126894567 @default.
• W1978040069 hasConceptScore W1978040069C134018914 @default.
• W1978040069 hasConceptScore W1978040069C159641895 @default.
• W1978040069 hasConceptScore W1978040069C178790620 @default.
• W1978040069 hasConceptScore W1978040069C185592680 @default.
• W1978040069 hasConceptScore W1978040069C2777214474 @default.
• W1978040069 hasConceptScore W1978040069C2777720800 @default.
• W1978040069 hasConceptScore W1978040069C2778674827 @default.
• W1978040069 hasConceptScore W1978040069C2778808290 @default.
• W1978040069 hasConceptScore W1978040069C2780325230 @default.
• W1978040069 hasConceptScore W1978040069C2780496750 @default.
• W1978040069 hasConceptScore W1978040069C2781033279 @default.
• W1978040069 hasConceptScore W1978040069C537181965 @default.
• W1978040069 hasConceptScore W1978040069C56900294 @default.
• W1978040069 hasConceptScore W1978040069C71924100 @default.
• W1978040069 hasConceptScore W1978040069C90924648 @default.
• W1978040069 hasIssue "3" @default.
• W1978040069 hasLocation W19780400691 @default.
• W1978040069 hasLocation W19780400692 @default.
• W1978040069 hasOpenAccess W1978040069 @default.
• W1978040069 hasPrimaryLocation W19780400691 @default.
• W1978040069 hasRelatedWork W203062747 @default.
• W1978040069 hasRelatedWork W2040818879 @default.
• W1978040069 hasRelatedWork W2071225816 @default.
• W1978040069 hasRelatedWork W2088144781 @default.
• W1978040069 hasRelatedWork W2121061473 @default.

• next