Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978063283> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1978063283 abstract "Valve replacement in children has always been associated with a high mortality, outgrowth of the prosthetic valve and difficulty in managing anticoagulation. Between January 1985 and April 1991, 20 patients (14 males and 6 females) underwent replacement of a left-sided cardiac valve. The median age at diagnosis was 21.6 months (1 to 120 months) and the median age at surgery was 85 months (11 to 213 months). Six patients were under 4 years of age. The site of valve replacement was aortic in 11 patients and left atrioventricular (AV) valve in 9 patients. The indications for aortic valve replacement were stenosis (6) and incompetence (5). The left AV valve was replaced in three patients following repair of AV septal defect, in one patient with corrected transposition of the great arteries (LTGA), in one patient with severe dysplasia and insufficiency, and in four patients for congenital mitral stenosis. A Bjork-Shiley prosthesis was used in three mitral and one aortic position, all the other patients receiving a St. Jude prosthesis: six mitral and ten aortic. All patients were anticoagulated (warfarin) for 3 months post implantation and then switched to a regimen of aspirin and persantine. There was no early or late death. Median follow-up was 12.3 months (4 to 72 months). Total follow-up was 59 patient-years or 708 months. There was one incident of thromboembolism (1.7%/patient-year) and four instances of bleeding (6.8%/patient-year). There was no valve thrombosis. Our regime of early warfarin followed by long-term antiplatelet therapy has been associated with a low incidence of thromboembolism and no valve thrombosis." @default.
- W1978063283 created "2016-06-24" @default.
- W1978063283 creator A5001229233 @default.
- W1978063283 creator A5043864731 @default.
- W1978063283 creator A5088836602 @default.
- W1978063283 date "1993-01-01" @default.
- W1978063283 modified "2023-09-27" @default.
- W1978063283 title "Antiplatelet therapy in children with left-sided mechanical prostheses" @default.
- W1978063283 cites W137759514 @default.
- W1978063283 cites W172827979 @default.
- W1978063283 cites W1970618928 @default.
- W1978063283 cites W1974607182 @default.
- W1978063283 cites W1975986470 @default.
- W1978063283 cites W1987643889 @default.
- W1978063283 cites W1987927838 @default.
- W1978063283 cites W2018214089 @default.
- W1978063283 cites W2048488358 @default.
- W1978063283 cites W2131714067 @default.
- W1978063283 cites W2166458827 @default.
- W1978063283 cites W2337130116 @default.
- W1978063283 cites W2396117422 @default.
- W1978063283 cites W2399567456 @default.
- W1978063283 cites W2402594068 @default.
- W1978063283 cites W2410437203 @default.
- W1978063283 cites W2412606468 @default.
- W1978063283 cites W2415154495 @default.
- W1978063283 cites W2417074158 @default.
- W1978063283 cites W2419042498 @default.
- W1978063283 cites W2460706701 @default.
- W1978063283 cites W94861547 @default.
- W1978063283 doi "https://doi.org/10.1016/1010-7940(93)90161-4" @default.
- W1978063283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8481259" @default.
- W1978063283 hasPublicationYear "1993" @default.
- W1978063283 type Work @default.
- W1978063283 sameAs 1978063283 @default.
- W1978063283 citedByCount "15" @default.
- W1978063283 countsByYear W19780632832012 @default.
- W1978063283 countsByYear W19780632832013 @default.
- W1978063283 crossrefType "journal-article" @default.
- W1978063283 hasAuthorship W1978063283A5001229233 @default.
- W1978063283 hasAuthorship W1978063283A5043864731 @default.
- W1978063283 hasAuthorship W1978063283A5088836602 @default.
- W1978063283 hasConcept C126322002 @default.
- W1978063283 hasConcept C141071460 @default.
- W1978063283 hasConcept C164705383 @default.
- W1978063283 hasConcept C2775854548 @default.
- W1978063283 hasConcept C2776301958 @default.
- W1978063283 hasConcept C2776570981 @default.
- W1978063283 hasConcept C2777543888 @default.
- W1978063283 hasConcept C2778715743 @default.
- W1978063283 hasConcept C2779161974 @default.
- W1978063283 hasConcept C2780007028 @default.
- W1978063283 hasConcept C2780868729 @default.
- W1978063283 hasConcept C71924100 @default.
- W1978063283 hasConceptScore W1978063283C126322002 @default.
- W1978063283 hasConceptScore W1978063283C141071460 @default.
- W1978063283 hasConceptScore W1978063283C164705383 @default.
- W1978063283 hasConceptScore W1978063283C2775854548 @default.
- W1978063283 hasConceptScore W1978063283C2776301958 @default.
- W1978063283 hasConceptScore W1978063283C2776570981 @default.
- W1978063283 hasConceptScore W1978063283C2777543888 @default.
- W1978063283 hasConceptScore W1978063283C2778715743 @default.
- W1978063283 hasConceptScore W1978063283C2779161974 @default.
- W1978063283 hasConceptScore W1978063283C2780007028 @default.
- W1978063283 hasConceptScore W1978063283C2780868729 @default.
- W1978063283 hasConceptScore W1978063283C71924100 @default.
- W1978063283 hasLocation W19780632831 @default.
- W1978063283 hasLocation W19780632832 @default.
- W1978063283 hasOpenAccess W1978063283 @default.
- W1978063283 hasPrimaryLocation W19780632831 @default.
- W1978063283 hasRelatedWork W1592760905 @default.
- W1978063283 hasRelatedWork W1964666267 @default.
- W1978063283 hasRelatedWork W1978063283 @default.
- W1978063283 hasRelatedWork W1983037022 @default.
- W1978063283 hasRelatedWork W2004143240 @default.
- W1978063283 hasRelatedWork W2035316524 @default.
- W1978063283 hasRelatedWork W2096877623 @default.
- W1978063283 hasRelatedWork W2401195792 @default.
- W1978063283 hasRelatedWork W2402357616 @default.
- W1978063283 hasRelatedWork W2425598749 @default.
- W1978063283 isParatext "false" @default.
- W1978063283 isRetracted "false" @default.
- W1978063283 magId "1978063283" @default.
- W1978063283 workType "article" @default.