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• W1978090494 abstract "Previously, it has been shown that · NO donor S ‐nitrosoglutathione (GSNO) improves the postischemic functional recovery in crystalloid buffer‐perfused isolated rat hearts subjected to cardioplegic ischemia. Supplementation of cardioplegic solution with nitronyl nitroxide, a scavenger of · NO, antagonized this protective effect. Using low temperature ESR, we have detected nitrosylmyoglobin (MbNO) in rat hearts subjected to cardioplegic ischemia in the presence of GSNO (20–200 μmol/l). During aerobic reperfusion MbNO signal intensity gradually decreased, but persisted for up to 30 min of aerobic reperfusion. We conclude that MbNO is an endogenous marker of · NO release in myocardial tissues. Implications of MbNO formation are discussed with respect to cardioprotection during ischemia‐ and reperfusion‐induced myocardial injury." @default.
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• W1978090494 date "1996-01-08" @default.
• W1978090494 modified "2023-10-17" @default.
• W1978090494 title "<i>S</i>‐Nitrosoglutathione induces formation of nitrosylmyoglobin in isolated hearts during cardioplegic ischemia — an electron spin resonance study" @default.
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• W1978090494 doi "https://doi.org/10.1016/0014-5793(95)01429-2" @default.
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