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- W1978096989 abstract "The in vivo effects of ethidium bromide on the integrity of mitochondrial DNA have been studied in a mouse L-cell system in which this DNA may be nearly exclusively radiolabelled. This allows the detection of mitochondrial DNA in the presence of contaminating nuclear DNA and eliminates the need for extensive purification of mitochondria or the use of deoxyribonuclease. The mitochondrial DNA in treated cells rapidly attains a high negative superhelix density and is not substantially nicked or degraded over the course of several days." @default.
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- W1978096989 date "1977-01-01" @default.
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- W1978096989 title "Absence of ethidium bromide induced nicking and degradation of mitochondrial DNA in mouse L-cells" @default.
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- W1978096989 doi "https://doi.org/10.1093/nar/4.5.1419" @default.
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