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• W1978121495 abstract "Copper is an essential nutrient for most life forms, however in excess it can be harmful. The ATP-driven copper pumps (Copper-ATPases) play critical role in living organisms by maintaining appropriate copper levels in cells and tissues. These evolutionary conserved polytopic membrane proteins are present in all phyla from simplest life forms (bacteria) to highly evolved eukaryotes (Homo sapiens). The presumed early function in metal detoxification remains the main function of Copper-ATPases in prokaryotic kingdom. In eukaryotes, in addition to removing excess copper from the cell, Copper-ATPases have another equally important function - to supply copper to copper dependent enzymes within the secretory pathway. This review focuses on the origin and diversification of Copper ATPases in eukaryotic organisms. From a single Copper ATPase in protozoans, a divergence into two functionally distinct ATPases is observed with the evolutionary appearance of chordates. Among the key functional domains of Copper-ATPases, the metal-binding N-terminal domain could be responsible for functional diversification of the copper ATPases during the course of evolution." @default.
• W1978121495 created "2016-06-24" @default.
• W1978121495 creator A5074008091 @default.
• W1978121495 creator A5079179187 @default.
• W1978121495 date "2012-04-03" @default.
• W1978121495 modified "2023-09-26" @default.
• W1978121495 title "Evolution of Copper Transporting ATPases in Eukaryotic Organisms" @default.
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• W1978121495 cites W1979323699 @default.
• W1978121495 cites W1980443589 @default.
• W1978121495 cites W1982243317 @default.
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• W1978121495 doi "https://doi.org/10.2174/138920212799860661" @default.
• W1978121495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3308323" @default.
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• W1978121495 hasPublicationYear "2012" @default.
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