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- W1978135753 abstract "From recent progress in cancer research, the hypothesis has been proposed that cancer cells have the ability to produce growth factors and to stimulate tumorigenesis by responding to these factors. This mechanism is now known as the autocrine growth mechanism of cancer cells, and factors responsible for this mechanism are called autocrine growth factors. 1 Sporn MB Roberts AB Autocrine growth factors and cancer. Nature. 1985; 313: 745-747 Crossref PubMed Scopus (1136) Google Scholar We have recently examined biologic and clinical implications of possible autocrine growth factors for lung cancers. Here, we review our observations indicating that transforming growth factor, TGFα, is a possible autocrine growth factor for lung adenocarcinoma and that gastrin-releasing peptide (GRP) could serve as a reliable tumor marker for patients with small cell lung carcinoma (SCLC)." @default.
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- W1978135753 date "1989-07-01" @default.
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- W1978135753 title "Lung Cancer and Autocrine Growth Factors" @default.
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- W1978135753 doi "https://doi.org/10.1378/chest.96.1_supplement.29s" @default.
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