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- W1978154189 abstract "Therapeutic hypothermia is now regarded as the only effective treatment of global ischemic injury following cardiac arrest or airway obstruction. However, the clinical trials with individual neuroprotective drugs given after transient global cerebral ischemia performed to date have failed to demonstrate improved neurological outcomes. Numerous studies of the effects of 17β-estradiol have yielded conflicting results depending on administration route and dose. Furthermore, combination treatments of hypothermia and many neuroprotective drugs have been studied, although not 17β-estradiol. Herein, we investigated the neuroprotective effect of post-ischemic 17β-estradiol administration combined with therapeutic hypothermia." @default.
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- W1978154189 date "2012-11-01" @default.
- W1978154189 modified "2023-09-27" @default.
- W1978154189 title "Combination Treatment with 17β-estradiol and Therapeutic Hypothermia for Transient Global Cerebral Ischemia in Rats" @default.
- W1978154189 doi "https://doi.org/10.1016/j.jemermed.2012.09.123" @default.
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