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• W1978162889 endingPage "190" @default.
• W1978162889 startingPage "184" @default.
• W1978162889 abstract "Abstract: Liver transplantation (OLT) recipients who receive a graft from donors positive for hepatitis B virus (HBV) anti‐core antibodies may develop overt “ de novo ” HBV infection. The study was undertaken to explore how often HBV infection may remain occult after OLT for hepatitis C, and whether it may represent a factor of graft fibrosis progression. We studied 30 consecutive patients transplanted for hepatitis C liver disease. Specimens from the native liver and from the graft were searched for occult HBV infection (O‐HBV). In the native liver, 8/30 patients had detectable O‐HBV; during the follow‐up, O‐HBV infection was demonstrated in 14 graft specimens. Graft O‐HBV was associated with older donor age (≥50 yr; 8/9 vs. 6/21, p < 0.005). Recipients with graft O‐HBV and no O‐HBV in the native liver who received their grafts from donors aged >40 yr had faster fibrosis progression than recipients with no post‐transplant O‐HBV, whose grafts came from donors aged >40 yr and recipients whose grafts came from donors aged ≤40 yr (4/7 vs. 1/7 vs. 2/16, p < 0.05). In OLT recipients, O‐HBV is more likely to occur when grafts are obtained from aged donors and may affect the rate of fibrosis progression because of recurrent hepatitis C." @default.
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• W1978162889 date "2009-03-01" @default.
• W1978162889 modified "2023-10-10" @default.
• W1978162889 title "Occult hepatitis B virus infection in liver transplant recipients with recurrent hepatitis C: relationship with donor age and fibrosis progression" @default.
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• W1978162889 doi "https://doi.org/10.1111/j.1399-0012.2009.00964.x" @default.
• W1978162889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19210526" @default.
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