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• W1978163354 abstract "A comparative analysis of the effects of externally applied Rb+, Cs+, Sr2+, Ba2+ and La3+ on myelinated fibres under potential clamp conditions was made. The ions Cs+, Ba2+ and La:l+ (belonging to groups 1a, 2a and 3a of period 6 in the periodic system) were found to affect the K system in specific ways. Ba2+ and La3+ reduced the outward K+ current associated with positive potential steps; the effect of La3+ being larger than that of Ba2+. The effect of Ba2+ depended on the K+ concentration. Cs+, Ba2+ and La3+ reduced the inward K+ tail current at repolarisation in solutions with high K+ concentration. Cs+ and Ba2+ caused a rectification of the K+ current, i.e. they reduced the inward tail current proportionally more than the outward steady state current. The effect of Baz+ could not be described as a simple reduction of the permeability constant p¯K. Rb+ was found to affect the time course of the K system by increasing the rate constant βn. Sr2*, Ba2+ and La3+ reduced the permeability constant p¯Na. These ions also shifted potential dependent parameters in general along the potential axis. The effect of La3+ was larger than that of Sr2+ and Ba2+. Cs2+, Ba2+ and La3+ reduced the p-current, Ba2+ and La3+ the leak conductance." @default.
• W1978163354 created "2016-06-24" @default.
• W1978163354 creator A5090713829 @default.
• W1978163354 date "1980-01-01" @default.
• W1978163354 modified "2023-10-05" @default.
• W1978163354 title "Effects of rubidium, caesium, strontium, barium and lanthanum on ionic currents in myelinated nerve fibres fromXenopus laevis" @default.
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• W1978163354 doi "https://doi.org/10.1111/j.1748-1716.1980.tb06494.x" @default.
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