FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978165103> ?p ?o ?g. }

• W1978165103 endingPage "116" @default.
• W1978165103 startingPage "112" @default.
• W1978165103 abstract "Band 3 is a transmembrane protein of erythrocytes and its cytosolic part regulates glucose metabolism to proceed along the pentose phosphate pathway (PPP) or glycolytic pathway by binding with the central cavity of the β chain of deoxygenated hemoglobin and with some glycolytic enzymes competitively. In β thalassemia major and hemoglobin (Hb)Eβ thalassemia, β chain is either absent or distorted and glucose metabolism may be disturbed. We estimated adenosine triphosphate (ATP), glucose 6-phosphate dehydrogenase (G6PD) and aldolase activity in oxygenated and deoxygenated state of erythrocytes of β major, HbEβ thalassemia and normal controls to understand the hypothesis that major glucose metabolism within the erythrocytes of these diseases may proceed through the PPP. Fifty of each group of patients and 52 normal controls were included. Patients' blood was collected 1 month prior to blood transfusion. G6PD and aldolase were estimated using a commercial kit. ATP was measured by spectrophotometric method. Significantly low levels of erythrocytic ATP and higher levels of G6PD were found in two groups of patients. Aldolase level in deoxygenated hemolysate was significantly higher than oxygenated hemolysate in normal controls but no significant change was noticed in both types of thalassemic patients. In β thalassemia major and HbEβ thalassemia due to distortion of β chain, binding of deoxygenated hemoglobin with band 3 is inhibited and thus traffic control of glycolytic pathway is disturbed and shifted towards PPP." @default.
• W1978165103 created "2016-06-24" @default.
• W1978165103 creator A5004166831 @default.
• W1978165103 creator A5064936646 @default.
• W1978165103 creator A5078374399 @default.
• W1978165103 creator A5088180170 @default.
• W1978165103 date "2012-02-01" @default.
• W1978165103 modified "2023-09-25" @default.
• W1978165103 title "Distortion of β-globin Chain of Hemoglobin Alters the Pathway of Erythrocytic Glucose Metabolism Through Band 3 Protein" @default.
• W1978165103 cites W1554532255 @default.
• W1978165103 cites W1561589021 @default.
• W1978165103 cites W1870391416 @default.
• W1978165103 cites W1964299129 @default.
• W1978165103 cites W1967694347 @default.
• W1978165103 cites W1978439292 @default.
• W1978165103 cites W1982899101 @default.
• W1978165103 cites W1985811899 @default.
• W1978165103 cites W1986645079 @default.
• W1978165103 cites W2021868083 @default.
• W1978165103 cites W2044596656 @default.
• W1978165103 cites W2061990569 @default.
• W1978165103 cites W2064119442 @default.
• W1978165103 cites W2073879684 @default.
• W1978165103 cites W2129709903 @default.
• W1978165103 cites W2157561719 @default.
• W1978165103 cites W2334749526 @default.
• W1978165103 cites W2405324 @default.
• W1978165103 cites W53980247 @default.
• W1978165103 doi "https://doi.org/10.1016/j.arcmed.2012.02.003" @default.
• W1978165103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22374247" @default.
• W1978165103 hasPublicationYear "2012" @default.
• W1978165103 type Work @default.
• W1978165103 sameAs 1978165103 @default.
• W1978165103 citedByCount "6" @default.
• W1978165103 countsByYear W19781651032017 @default.
• W1978165103 countsByYear W19781651032021 @default.
• W1978165103 countsByYear W19781651032022 @default.
• W1978165103 countsByYear W19781651032023 @default.
• W1978165103 crossrefType "journal-article" @default.
• W1978165103 hasAuthorship W1978165103A5004166831 @default.
• W1978165103 hasAuthorship W1978165103A5064936646 @default.
• W1978165103 hasAuthorship W1978165103A5078374399 @default.
• W1978165103 hasAuthorship W1978165103A5088180170 @default.
• W1978165103 hasConcept C122245378 @default.
• W1978165103 hasConcept C126322002 @default.
• W1978165103 hasConcept C134018914 @default.
• W1978165103 hasConcept C181199279 @default.
• W1978165103 hasConcept C185592680 @default.
• W1978165103 hasConcept C20251656 @default.
• W1978165103 hasConcept C2776317432 @default.
• W1978165103 hasConcept C2777799968 @default.
• W1978165103 hasConcept C2778917026 @default.
• W1978165103 hasConcept C2779372652 @default.
• W1978165103 hasConcept C2779564974 @default.
• W1978165103 hasConcept C28165981 @default.
• W1978165103 hasConcept C3409486 @default.
• W1978165103 hasConcept C3488265 @default.
• W1978165103 hasConcept C55493867 @default.
• W1978165103 hasConcept C62231903 @default.
• W1978165103 hasConcept C71924100 @default.
• W1978165103 hasConcept C86803240 @default.
• W1978165103 hasConceptScore W1978165103C122245378 @default.
• W1978165103 hasConceptScore W1978165103C126322002 @default.
• W1978165103 hasConceptScore W1978165103C134018914 @default.
• W1978165103 hasConceptScore W1978165103C181199279 @default.
• W1978165103 hasConceptScore W1978165103C185592680 @default.
• W1978165103 hasConceptScore W1978165103C20251656 @default.
• W1978165103 hasConceptScore W1978165103C2776317432 @default.
• W1978165103 hasConceptScore W1978165103C2777799968 @default.
• W1978165103 hasConceptScore W1978165103C2778917026 @default.
• W1978165103 hasConceptScore W1978165103C2779372652 @default.
• W1978165103 hasConceptScore W1978165103C2779564974 @default.
• W1978165103 hasConceptScore W1978165103C28165981 @default.
• W1978165103 hasConceptScore W1978165103C3409486 @default.
• W1978165103 hasConceptScore W1978165103C3488265 @default.
• W1978165103 hasConceptScore W1978165103C55493867 @default.
• W1978165103 hasConceptScore W1978165103C62231903 @default.
• W1978165103 hasConceptScore W1978165103C71924100 @default.
• W1978165103 hasConceptScore W1978165103C86803240 @default.
• W1978165103 hasIssue "2" @default.
• W1978165103 hasLocation W19781651031 @default.
• W1978165103 hasLocation W19781651032 @default.
• W1978165103 hasOpenAccess W1978165103 @default.
• W1978165103 hasPrimaryLocation W19781651031 @default.
• W1978165103 hasRelatedWork W1978165103 @default.
• W1978165103 hasRelatedWork W2011095916 @default.
• W1978165103 hasRelatedWork W2013713538 @default.
• W1978165103 hasRelatedWork W2014184142 @default.
• W1978165103 hasRelatedWork W2032947420 @default.
• W1978165103 hasRelatedWork W2092330693 @default.
• W1978165103 hasRelatedWork W2106302191 @default.
• W1978165103 hasRelatedWork W2411034606 @default.
• W1978165103 hasRelatedWork W2416660564 @default.
• W1978165103 hasRelatedWork W2417574311 @default.
• W1978165103 hasVolume "43" @default.
• W1978165103 isParatext "false" @default.
• W1978165103 isRetracted "false" @default.
• W1978165103 magId "1978165103" @default.

• next