Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978194803> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1978194803 endingPage "173" @default.
- W1978194803 startingPage "171" @default.
- W1978194803 abstract "Patients with brain tumors and seizures should be treated with non-enzyme-inducing antiepileptic drugs (AED). Some of the newer drugs seem particularly suited in these patients.Here we describe our experience with pregabalin (PGB); its effectiveness was retrospectively studied in nine consecutive patients with primary brain tumors and seizures.Six subjects had secondarily generalized and three simple partial seizures. Patients mostly suffered from WHO grade IV gliomas. PGB replaced enzyme inducing, inefficacious or bad tolerated AED, as add-on or monotherapy. Median follow-up was 5 (2-19) months; three patients died of their tumor. Daily median dosage was 300 mg. All subjects experienced at least a 50% seizure reduction, six were seizure-free. Side effects were reported in four patients, leading to PGB discontinuation in two.PGB appears to have a promising effectiveness in this setting, even as a monotherapy. Based on these results we embarked on a prospective controlled trial." @default.
- W1978194803 created "2016-06-24" @default.
- W1978194803 creator A5000322729 @default.
- W1978194803 creator A5003722970 @default.
- W1978194803 creator A5053052330 @default.
- W1978194803 date "2009-02-01" @default.
- W1978194803 modified "2023-10-16" @default.
- W1978194803 title "Pregabalin in patients with primary brain tumors and seizures: A preliminary observation" @default.
- W1978194803 cites W1990516454 @default.
- W1978194803 cites W2005018772 @default.
- W1978194803 cites W2013772421 @default.
- W1978194803 cites W2014576747 @default.
- W1978194803 cites W2029867107 @default.
- W1978194803 cites W2033369193 @default.
- W1978194803 cites W2038376591 @default.
- W1978194803 cites W2046755618 @default.
- W1978194803 cites W2049838912 @default.
- W1978194803 cites W2055427394 @default.
- W1978194803 cites W2059367843 @default.
- W1978194803 cites W2061839656 @default.
- W1978194803 cites W2076516150 @default.
- W1978194803 cites W2078789079 @default.
- W1978194803 cites W2078797427 @default.
- W1978194803 cites W2098070766 @default.
- W1978194803 cites W2100990673 @default.
- W1978194803 cites W2111042597 @default.
- W1978194803 cites W2125397400 @default.
- W1978194803 cites W2143671301 @default.
- W1978194803 cites W2160893557 @default.
- W1978194803 cites W2163642916 @default.
- W1978194803 cites W2189037963 @default.
- W1978194803 cites W4248307879 @default.
- W1978194803 cites W83394720 @default.
- W1978194803 doi "https://doi.org/10.1016/j.clineuro.2008.09.009" @default.
- W1978194803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18977587" @default.
- W1978194803 hasPublicationYear "2009" @default.
- W1978194803 type Work @default.
- W1978194803 sameAs 1978194803 @default.
- W1978194803 citedByCount "42" @default.
- W1978194803 countsByYear W19781948032012 @default.
- W1978194803 countsByYear W19781948032013 @default.
- W1978194803 countsByYear W19781948032014 @default.
- W1978194803 countsByYear W19781948032015 @default.
- W1978194803 countsByYear W19781948032016 @default.
- W1978194803 countsByYear W19781948032018 @default.
- W1978194803 countsByYear W19781948032019 @default.
- W1978194803 countsByYear W19781948032020 @default.
- W1978194803 countsByYear W19781948032021 @default.
- W1978194803 crossrefType "journal-article" @default.
- W1978194803 hasAuthorship W1978194803A5000322729 @default.
- W1978194803 hasAuthorship W1978194803A5003722970 @default.
- W1978194803 hasAuthorship W1978194803A5053052330 @default.
- W1978194803 hasConcept C118552586 @default.
- W1978194803 hasConcept C126322002 @default.
- W1978194803 hasConcept C142724271 @default.
- W1978194803 hasConcept C187212893 @default.
- W1978194803 hasConcept C2776468701 @default.
- W1978194803 hasConcept C2777803345 @default.
- W1978194803 hasConcept C2778186239 @default.
- W1978194803 hasConcept C2778715236 @default.
- W1978194803 hasConcept C2779130545 @default.
- W1978194803 hasConcept C42219234 @default.
- W1978194803 hasConcept C71924100 @default.
- W1978194803 hasConceptScore W1978194803C118552586 @default.
- W1978194803 hasConceptScore W1978194803C126322002 @default.
- W1978194803 hasConceptScore W1978194803C142724271 @default.
- W1978194803 hasConceptScore W1978194803C187212893 @default.
- W1978194803 hasConceptScore W1978194803C2776468701 @default.
- W1978194803 hasConceptScore W1978194803C2777803345 @default.
- W1978194803 hasConceptScore W1978194803C2778186239 @default.
- W1978194803 hasConceptScore W1978194803C2778715236 @default.
- W1978194803 hasConceptScore W1978194803C2779130545 @default.
- W1978194803 hasConceptScore W1978194803C42219234 @default.
- W1978194803 hasConceptScore W1978194803C71924100 @default.
- W1978194803 hasIssue "2" @default.
- W1978194803 hasLocation W19781948031 @default.
- W1978194803 hasLocation W19781948032 @default.
- W1978194803 hasOpenAccess W1978194803 @default.
- W1978194803 hasPrimaryLocation W19781948031 @default.
- W1978194803 hasRelatedWork W193971483 @default.
- W1978194803 hasRelatedWork W1975953218 @default.
- W1978194803 hasRelatedWork W2012649957 @default.
- W1978194803 hasRelatedWork W2073028005 @default.
- W1978194803 hasRelatedWork W2119629508 @default.
- W1978194803 hasRelatedWork W2356443853 @default.
- W1978194803 hasRelatedWork W2363907062 @default.
- W1978194803 hasRelatedWork W2393137063 @default.
- W1978194803 hasRelatedWork W2530540509 @default.
- W1978194803 hasRelatedWork W2896589794 @default.
- W1978194803 hasVolume "111" @default.
- W1978194803 isParatext "false" @default.
- W1978194803 isRetracted "false" @default.
- W1978194803 magId "1978194803" @default.
- W1978194803 workType "article" @default.