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- W1978201405 abstract "Purpose: Our objective was to apply ooplasmic round spermatid nuclear injections for the treatment of nonobstructive azoospermia. Materials: Participants were nine azoospermic men who had previously undergone diagnostic testicular biopsy. Spermatogenetic arrest was diagnosed at the round spermatid stage (n=6) or primary spermatocyte stage (n=3). A second (therapeutic) testicular biopsy was performed and round spermatid nuclei were recovered from all the participants. Results: Forty-nine mature oocytes were successfully injected with nuclei and then cultured for 72 hr. Twenty-four embryos were transferred to nine women. No pregnancy was achieved. Conclusions: Round spermatids can be recovered from therapeutic testicular biopsy material of men negative for round spermatids in previous routine diagnostic testicular biopsy specimens. Round spermatid nuclear injections may play a role in the treatment of nonobstructive azoospermia." @default.
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- W1978201405 date "1997-01-01" @default.
- W1978201405 modified "2023-10-11" @default.
- W1978201405 title "Ooplasmic round spermatid nuclear injection procedures as an experimental treatment for nonobstructive azoospermia" @default.
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- W1978201405 doi "https://doi.org/10.1007/bf02765754" @default.
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