FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978201437> ?p ?o ?g. }

• W1978201437 endingPage "249" @default.
• W1978201437 startingPage "244" @default.
• W1978201437 abstract "Immunomodulation of natural polysaccharides has been the hot topic of research in recent years. In order to explore the immunomodulatory effect of Houttuynia cordata Thunb., the water extract was studied and a polysaccharide HCP-2 with molecular weight of 60,000 Da was isolated by chromatography using DEAE Sepharose CL-6B and Sephacryl S-500 [corrected] HR columns. The structure characterization of HCP-2 was performed by Fourier transform infrared spectroscopy (FTIR), acidic hydrolysis, PMP derivation, HPLC analysis and nuclear magnetic resonance spectra (NMR). HCP-2 was elucidated as a pectic polysaccharide with a linear chain of 1,4-linked α-D-galacturonic acid residues in which part of the 6-carboxyl groups were methyl esterified and part of 2-hydroxyl groups were acetylated. The bioactivity assays showed that HCP-2 could increase the secretions of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), macrophage inhibitory protein-1α (MIP-1α), macrophage inhibitory protein-1β (MIP-1β), and RANTES (regulated on activation, normal T cell expressed and secreted) in human peripheral blood mononuclear cells (PBMCs), which play critical roles in the innate immune system and shape the adaptive immunity. Our results implied that HCP-2 could be an immune enhancer." @default.
• W1978201437 created "2016-06-24" @default.
• W1978201437 creator A5002582581 @default.
• W1978201437 creator A5009913628 @default.
• W1978201437 creator A5012697645 @default.
• W1978201437 creator A5015038302 @default.
• W1978201437 creator A5032386807 @default.
• W1978201437 creator A5041465938 @default.
• W1978201437 creator A5066810178 @default.
• W1978201437 creator A5067873183 @default.
• W1978201437 creator A5074109308 @default.
• W1978201437 creator A5087822712 @default.
• W1978201437 creator A5090600960 @default.
• W1978201437 date "2014-03-01" @default.
• W1978201437 modified "2023-10-14" @default.
• W1978201437 title "Structural characterization and immunomodulatory effect of a polysaccharide HCP-2 from Houttuynia cordata" @default.
• W1978201437 cites W1975061448 @default.
• W1978201437 cites W1982228065 @default.
• W1978201437 cites W1988940275 @default.
• W1978201437 cites W1993116258 @default.
• W1978201437 cites W1995151702 @default.
• W1978201437 cites W1995443419 @default.
• W1978201437 cites W2017046983 @default.
• W1978201437 cites W2031740480 @default.
• W1978201437 cites W2041378377 @default.
• W1978201437 cites W2043990601 @default.
• W1978201437 cites W2045409581 @default.
• W1978201437 cites W2057234379 @default.
• W1978201437 cites W2059674129 @default.
• W1978201437 cites W2062835892 @default.
• W1978201437 cites W2062898092 @default.
• W1978201437 cites W2063709720 @default.
• W1978201437 cites W2068126399 @default.
• W1978201437 cites W2071613278 @default.
• W1978201437 cites W2072291431 @default.
• W1978201437 cites W2089816757 @default.
• W1978201437 cites W2106728647 @default.
• W1978201437 cites W2107958058 @default.
• W1978201437 cites W2159759448 @default.
• W1978201437 cites W2166894611 @default.
• W1978201437 doi "https://doi.org/10.1016/j.carbpol.2013.12.048" @default.
• W1978201437 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7112369" @default.
• W1978201437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24528726" @default.
• W1978201437 hasPublicationYear "2014" @default.
• W1978201437 type Work @default.
• W1978201437 sameAs 1978201437 @default.
• W1978201437 citedByCount "37" @default.
• W1978201437 countsByYear W19782014372014 @default.
• W1978201437 countsByYear W19782014372015 @default.
• W1978201437 countsByYear W19782014372016 @default.
• W1978201437 countsByYear W19782014372017 @default.
• W1978201437 countsByYear W19782014372018 @default.
• W1978201437 countsByYear W19782014372019 @default.
• W1978201437 countsByYear W19782014372020 @default.
• W1978201437 countsByYear W19782014372021 @default.
• W1978201437 countsByYear W19782014372022 @default.
• W1978201437 countsByYear W19782014372023 @default.
• W1978201437 crossrefType "journal-article" @default.
• W1978201437 hasAuthorship W1978201437A5002582581 @default.
• W1978201437 hasAuthorship W1978201437A5009913628 @default.
• W1978201437 hasAuthorship W1978201437A5012697645 @default.
• W1978201437 hasAuthorship W1978201437A5015038302 @default.
• W1978201437 hasAuthorship W1978201437A5032386807 @default.
• W1978201437 hasAuthorship W1978201437A5041465938 @default.
• W1978201437 hasAuthorship W1978201437A5066810178 @default.
• W1978201437 hasAuthorship W1978201437A5067873183 @default.
• W1978201437 hasAuthorship W1978201437A5074109308 @default.
• W1978201437 hasAuthorship W1978201437A5087822712 @default.
• W1978201437 hasAuthorship W1978201437A5090600960 @default.
• W1978201437 hasBestOaLocation W19782014371 @default.
• W1978201437 hasConcept C100817775 @default.
• W1978201437 hasConcept C136449434 @default.
• W1978201437 hasConcept C137061746 @default.
• W1978201437 hasConcept C170493617 @default.
• W1978201437 hasConcept C17991360 @default.
• W1978201437 hasConcept C185592680 @default.
• W1978201437 hasConcept C202751555 @default.
• W1978201437 hasConcept C203014093 @default.
• W1978201437 hasConcept C2776086038 @default.
• W1978201437 hasConcept C43617362 @default.
• W1978201437 hasConcept C4725764 @default.
• W1978201437 hasConcept C55493867 @default.
• W1978201437 hasConcept C86803240 @default.
• W1978201437 hasConcept C8891405 @default.
• W1978201437 hasConcept C94412978 @default.
• W1978201437 hasConceptScore W1978201437C100817775 @default.
• W1978201437 hasConceptScore W1978201437C136449434 @default.
• W1978201437 hasConceptScore W1978201437C137061746 @default.
• W1978201437 hasConceptScore W1978201437C170493617 @default.
• W1978201437 hasConceptScore W1978201437C17991360 @default.
• W1978201437 hasConceptScore W1978201437C185592680 @default.
• W1978201437 hasConceptScore W1978201437C202751555 @default.
• W1978201437 hasConceptScore W1978201437C203014093 @default.
• W1978201437 hasConceptScore W1978201437C2776086038 @default.
• W1978201437 hasConceptScore W1978201437C43617362 @default.
• W1978201437 hasConceptScore W1978201437C4725764 @default.
• W1978201437 hasConceptScore W1978201437C55493867 @default.
• W1978201437 hasConceptScore W1978201437C86803240 @default.

• next