FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978233722> ?p ?o ?g. }

• W1978233722 endingPage "130" @default.
• W1978233722 startingPage "127" @default.
• W1978233722 abstract "A critical area of chromosomal loss at region p16(9p21-22) and p53(17p13) has been implicated in the genesis of malignant melanoma. It is still unclear whether the genetic alterations can be detected in dysplastic nevus, a premalignant lesion of malignant melanoma. We have searched the frequency of p16 and p53 deletion in nine dysplastic nevi and 13 benign intradermal nevi with five microsatellite markers. Hemizygous deletion was detected in seven of nine (78%) dysplastic nevi at one or more loci for p16 and three of seven (43%) for p53, respectively. No loss of heterozygosity (LOH) was detected in any of the benign intradermal nevi. All three dysplastic nevi with LOH for p53 also showed LOH at p16. However, not all dysplastic nevi showing p16 deletion showed p53 gene deletion. Therefore, these data suggest that deletion of p16 may play an important role in the development of dysplastic nevus as an early event and that the changes may represent an early event in the development of malignant melanoma." @default.
• W1978233722 created "2016-06-24" @default.
• W1978233722 creator A5005180335 @default.
• W1978233722 creator A5018041526 @default.
• W1978233722 creator A5018687194 @default.
• W1978233722 creator A5027488924 @default.
• W1978233722 creator A5042897178 @default.
• W1978233722 creator A5054112793 @default.
• W1978233722 creator A5056580634 @default.
• W1978233722 creator A5072545516 @default.
• W1978233722 creator A5086886026 @default.
• W1978233722 date "1998-02-01" @default.
• W1978233722 modified "2023-10-13" @default.
• W1978233722 title "Allelic deletion at chromosome 9p21(p16) and 17p13(p53) in microdissected sporadic dysplastic nevus" @default.
• W1978233722 cites W1983348452 @default.
• W1978233722 cites W1984988721 @default.
• W1978233722 cites W1994571309 @default.
• W1978233722 cites W1997073961 @default.
• W1978233722 cites W2010493387 @default.
• W1978233722 cites W2014522969 @default.
• W1978233722 cites W2035882662 @default.
• W1978233722 cites W2042316019 @default.
• W1978233722 cites W2043050258 @default.
• W1978233722 cites W2054549064 @default.
• W1978233722 cites W2062778449 @default.
• W1978233722 cites W2066848701 @default.
• W1978233722 cites W2067795112 @default.
• W1978233722 cites W2068289276 @default.
• W1978233722 cites W2076251317 @default.
• W1978233722 cites W2077768271 @default.
• W1978233722 cites W2083039819 @default.
• W1978233722 cites W2086773265 @default.
• W1978233722 cites W2135687675 @default.
• W1978233722 cites W2312531325 @default.
• W1978233722 cites W2320139078 @default.
• W1978233722 cites W4236702825 @default.
• W1978233722 cites W4238175378 @default.
• W1978233722 cites W4246198683 @default.
• W1978233722 cites W4249856106 @default.
• W1978233722 doi "https://doi.org/10.1016/s0046-8177(98)90221-0" @default.
• W1978233722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9490270" @default.
• W1978233722 hasPublicationYear "1998" @default.
• W1978233722 type Work @default.
• W1978233722 sameAs 1978233722 @default.
• W1978233722 citedByCount "82" @default.
• W1978233722 countsByYear W19782337222012 @default.
• W1978233722 countsByYear W19782337222014 @default.
• W1978233722 countsByYear W19782337222016 @default.
• W1978233722 countsByYear W19782337222017 @default.
• W1978233722 crossrefType "journal-article" @default.
• W1978233722 hasAuthorship W1978233722A5005180335 @default.
• W1978233722 hasAuthorship W1978233722A5018041526 @default.
• W1978233722 hasAuthorship W1978233722A5018687194 @default.
• W1978233722 hasAuthorship W1978233722A5027488924 @default.
• W1978233722 hasAuthorship W1978233722A5042897178 @default.
• W1978233722 hasAuthorship W1978233722A5054112793 @default.
• W1978233722 hasAuthorship W1978233722A5056580634 @default.
• W1978233722 hasAuthorship W1978233722A5072545516 @default.
• W1978233722 hasAuthorship W1978233722A5086886026 @default.
• W1978233722 hasConcept C104317684 @default.
• W1978233722 hasConcept C142724271 @default.
• W1978233722 hasConcept C143589142 @default.
• W1978233722 hasConcept C180754005 @default.
• W1978233722 hasConcept C2777377415 @default.
• W1978233722 hasConcept C2777658100 @default.
• W1978233722 hasConcept C2779323059 @default.
• W1978233722 hasConcept C502942594 @default.
• W1978233722 hasConcept C54355233 @default.
• W1978233722 hasConcept C71924100 @default.
• W1978233722 hasConcept C86803240 @default.
• W1978233722 hasConceptScore W1978233722C104317684 @default.
• W1978233722 hasConceptScore W1978233722C142724271 @default.
• W1978233722 hasConceptScore W1978233722C143589142 @default.
• W1978233722 hasConceptScore W1978233722C180754005 @default.
• W1978233722 hasConceptScore W1978233722C2777377415 @default.
• W1978233722 hasConceptScore W1978233722C2777658100 @default.
• W1978233722 hasConceptScore W1978233722C2779323059 @default.
• W1978233722 hasConceptScore W1978233722C502942594 @default.
• W1978233722 hasConceptScore W1978233722C54355233 @default.
• W1978233722 hasConceptScore W1978233722C71924100 @default.
• W1978233722 hasConceptScore W1978233722C86803240 @default.
• W1978233722 hasIssue "2" @default.
• W1978233722 hasLocation W19782337221 @default.
• W1978233722 hasLocation W19782337222 @default.
• W1978233722 hasOpenAccess W1978233722 @default.
• W1978233722 hasPrimaryLocation W19782337221 @default.
• W1978233722 hasRelatedWork W1573232374 @default.
• W1978233722 hasRelatedWork W1765894903 @default.
• W1978233722 hasRelatedWork W2012090310 @default.
• W1978233722 hasRelatedWork W2031628768 @default.
• W1978233722 hasRelatedWork W2046756125 @default.
• W1978233722 hasRelatedWork W2064195798 @default.
• W1978233722 hasRelatedWork W2085956481 @default.
• W1978233722 hasRelatedWork W2496178521 @default.
• W1978233722 hasRelatedWork W2565105143 @default.
• W1978233722 hasRelatedWork W4252912071 @default.
• W1978233722 hasVolume "29" @default.
• W1978233722 isParatext "false" @default.

• next