FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978240379> ?p ?o ?g. }

• W1978240379 endingPage "182" @default.
• W1978240379 startingPage "177" @default.
• W1978240379 abstract "The involvement of reactive oxygen species in Ca(2+)-induced mitochondrial membrane permeabilization and cell viability was studied using yeast cells in which the thioredoxin peroxidase (TPx) gene was disrupted and/or catalase was inhibited by 3-amino-1,2, 4-triazole (ATZ) treatment. Wild-type Saccharomyces cerevisiae cells were very resistant to Ca(2+) and inorganic phosphate or t-butyl hydroperoxide-induced mitochondrial membrane permeabilization, but suffered an immediate decrease in mitochondrial membrane potential when treated with Ca(2+) and the dithiol binding reagent phenylarsine oxide. In contrast, S. cerevisiae spheroblasts lacking the TPx gene and/or treated with ATZ suffered a decrease in mitochondrial membrane potential, generated higher amounts of hydrogen peroxide and had decreased viability under these conditions. In all cases, the decrease in mitochondrial membrane potential could be inhibited by ethylene glycol-bis(beta-aminoethyl ether) N,N, N',N'-tetraacetic acid, dithiothreitol or ADP, but not by cyclosporin A. We conclude that TPx and catalase act together, maintaining cell viability and protecting S. cerevisiae mitochondria against Ca(2+)-promoted membrane permeabilization, which presents similar characteristics to mammalian permeability transition." @default.
• W1978240379 created "2016-06-24" @default.
• W1978240379 creator A5004027759 @default.
• W1978240379 creator A5009718156 @default.
• W1978240379 creator A5020834497 @default.
• W1978240379 creator A5049076742 @default.
• W1978240379 date "2000-05-09" @default.
• W1978240379 modified "2023-09-30" @default.
• W1978240379 title "Catalases and thioredoxin peroxidase protect<i>Saccharomyces cerevisiae</i>against Ca²⁺-induced mitochondrial membrane permeabilization and cell death" @default.
• W1978240379 cites W1270671049 @default.
• W1978240379 cites W1487157100 @default.
• W1978240379 cites W1544998262 @default.
• W1978240379 cites W1583699416 @default.
• W1978240379 cites W1593734817 @default.
• W1978240379 cites W1598578622 @default.
• W1978240379 cites W1933556982 @default.
• W1978240379 cites W1963778474 @default.
• W1978240379 cites W1966687534 @default.
• W1978240379 cites W1966793349 @default.
• W1978240379 cites W1968112618 @default.
• W1978240379 cites W1970768581 @default.
• W1978240379 cites W1973129732 @default.
• W1978240379 cites W1979995768 @default.
• W1978240379 cites W1982733033 @default.
• W1978240379 cites W1986388339 @default.
• W1978240379 cites W1992282049 @default.
• W1978240379 cites W1997720526 @default.
• W1978240379 cites W2004110947 @default.
• W1978240379 cites W2009424100 @default.
• W1978240379 cites W2020524491 @default.
• W1978240379 cites W2025404996 @default.
• W1978240379 cites W2031057169 @default.
• W1978240379 cites W2036302841 @default.
• W1978240379 cites W2045951786 @default.
• W1978240379 cites W2051219590 @default.
• W1978240379 cites W2053534803 @default.
• W1978240379 cites W2057818847 @default.
• W1978240379 cites W2058992599 @default.
• W1978240379 cites W2061947498 @default.
• W1978240379 cites W2063385957 @default.
• W1978240379 cites W2069113458 @default.
• W1978240379 cites W2077227893 @default.
• W1978240379 cites W2079511086 @default.
• W1978240379 cites W2079513929 @default.
• W1978240379 cites W208281618 @default.
• W1978240379 cites W2088783542 @default.
• W1978240379 cites W2089062179 @default.
• W1978240379 cites W2109870797 @default.
• W1978240379 cites W2121702473 @default.
• W1978240379 cites W2130866079 @default.
• W1978240379 cites W2141260882 @default.
• W1978240379 cites W2148033110 @default.
• W1978240379 cites W2161898297 @default.
• W1978240379 cites W2163943333 @default.
• W1978240379 cites W4242497166 @default.
• W1978240379 cites W4253865768 @default.
• W1978240379 doi "https://doi.org/10.1016/s0014-5793(00)01526-x" @default.
• W1978240379 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10812070" @default.
• W1978240379 hasPublicationYear "2000" @default.
• W1978240379 type Work @default.
• W1978240379 sameAs 1978240379 @default.
• W1978240379 citedByCount "60" @default.
• W1978240379 countsByYear W19782403792012 @default.
• W1978240379 countsByYear W19782403792013 @default.
• W1978240379 countsByYear W19782403792014 @default.
• W1978240379 countsByYear W19782403792016 @default.
• W1978240379 countsByYear W19782403792017 @default.
• W1978240379 countsByYear W19782403792018 @default.
• W1978240379 countsByYear W19782403792020 @default.
• W1978240379 countsByYear W19782403792021 @default.
• W1978240379 countsByYear W19782403792022 @default.
• W1978240379 countsByYear W19782403792023 @default.
• W1978240379 crossrefType "journal-article" @default.
• W1978240379 hasAuthorship W1978240379A5004027759 @default.
• W1978240379 hasAuthorship W1978240379A5009718156 @default.
• W1978240379 hasAuthorship W1978240379A5020834497 @default.
• W1978240379 hasAuthorship W1978240379A5049076742 @default.
• W1978240379 hasConcept C13591479 @default.
• W1978240379 hasConcept C1491633281 @default.
• W1978240379 hasConcept C153911025 @default.
• W1978240379 hasConcept C181199279 @default.
• W1978240379 hasConcept C185592680 @default.
• W1978240379 hasConcept C190283241 @default.
• W1978240379 hasConcept C2776151105 @default.
• W1978240379 hasConcept C2777576037 @default.
• W1978240379 hasConcept C2777824588 @default.
• W1978240379 hasConcept C2778979269 @default.
• W1978240379 hasConcept C2779222958 @default.
• W1978240379 hasConcept C2781161309 @default.
• W1978240379 hasConcept C28859421 @default.
• W1978240379 hasConcept C31573885 @default.
• W1978240379 hasConcept C53227056 @default.
• W1978240379 hasConcept C55493867 @default.
• W1978240379 hasConcept C75385678 @default.
• W1978240379 hasConcept C86803240 @default.
• W1978240379 hasConceptScore W1978240379C13591479 @default.
• W1978240379 hasConceptScore W1978240379C1491633281 @default.
• W1978240379 hasConceptScore W1978240379C153911025 @default.

• next