FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978253166> ?p ?o ?g. }

• W1978253166 endingPage "1036" @default.
• W1978253166 startingPage "1032" @default.
• W1978253166 abstract "In this study, the antiproliferative effects of vinblastine (VLB), paclitaxel (TXL), doxorubicin (DXR), daunorubicin (DNR) and 5-fluorouracil (5-FU) were assessed in the human cervical carcinoma cell line HeLa-Ohio (HeLa) and Hvr100-6 cells, established by growing the parental HeLa cells in the presence of progressively greater concentrations of VLB in the culture medium. Flow cytometric analysis indicated the induction of MDR1 (P-glycoprotein) in Hvr100-6 cells with no alterations in levels of multidrug resistance-associated protein (MRP). Resistance to VLB, TXL, DXR and DNR was found in Hvr100-6 cells with relative resistances of ca. 300, 4000, 50 and 200, respectively, whereas no resistance was found to 5-FU. The reversal effects of antifungal drugs, fluconazole, itraconazole, ketoconazole, miconazole and amphotericin B on multidrug resistance were also assessed using Hvr100-6 cells. Itraconazole was found to have potent reversal effect on the resistance to VLB and TXL, but the others had no such effect. This reversal effect of itraconazole was concentration-dependent, with dose modifying factors of 3.2, 10.1 and 435.7 at 0.1, 0.25 and 0.5 μM of itraconazole, respectively. In addition, this reversal effect of itraconazole was explained by the inhibition of accumulation of the anticancer drugs." @default.
• W1978253166 created "2016-06-24" @default.
• W1978253166 creator A5000168284 @default.
• W1978253166 creator A5001104972 @default.
• W1978253166 creator A5001644765 @default.
• W1978253166 creator A5007760382 @default.
• W1978253166 creator A5017930456 @default.
• W1978253166 creator A5034908891 @default.
• W1978253166 creator A5039244520 @default.
• W1978253166 creator A5041584550 @default.
• W1978253166 creator A5057985584 @default.
• W1978253166 date "2001-01-01" @default.
• W1978253166 modified "2023-10-16" @default.
• W1978253166 title "Reversal Effects of Antifungal Drugs on Multidrug Resistance in MDR1-0verexpressing HeLa Cells." @default.
• W1978253166 cites W1496166354 @default.
• W1978253166 cites W1578896110 @default.
• W1978253166 cites W1964470226 @default.
• W1978253166 cites W1990594861 @default.
• W1978253166 cites W2005877531 @default.
• W1978253166 cites W2008579776 @default.
• W1978253166 cites W2016071165 @default.
• W1978253166 cites W2027445904 @default.
• W1978253166 cites W2044148793 @default.
• W1978253166 cites W2050609602 @default.
• W1978253166 cites W2076565275 @default.
• W1978253166 cites W2077510533 @default.
• W1978253166 cites W2102458361 @default.
• W1978253166 cites W2112001901 @default.
• W1978253166 cites W2127288395 @default.
• W1978253166 cites W2161663775 @default.
• W1978253166 cites W2403518551 @default.
• W1978253166 cites W4229897856 @default.
• W1978253166 doi "https://doi.org/10.1248/bpb.24.1032" @default.
• W1978253166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11558564" @default.
• W1978253166 hasPublicationYear "2001" @default.
• W1978253166 type Work @default.
• W1978253166 sameAs 1978253166 @default.
• W1978253166 citedByCount "35" @default.
• W1978253166 countsByYear W19782531662013 @default.
• W1978253166 countsByYear W19782531662014 @default.
• W1978253166 countsByYear W19782531662017 @default.
• W1978253166 countsByYear W19782531662018 @default.
• W1978253166 countsByYear W19782531662022 @default.
• W1978253166 crossrefType "journal-article" @default.
• W1978253166 hasAuthorship W1978253166A5000168284 @default.
• W1978253166 hasAuthorship W1978253166A5001104972 @default.
• W1978253166 hasAuthorship W1978253166A5001644765 @default.
• W1978253166 hasAuthorship W1978253166A5007760382 @default.
• W1978253166 hasAuthorship W1978253166A5017930456 @default.
• W1978253166 hasAuthorship W1978253166A5034908891 @default.
• W1978253166 hasAuthorship W1978253166A5039244520 @default.
• W1978253166 hasAuthorship W1978253166A5041584550 @default.
• W1978253166 hasAuthorship W1978253166A5057985584 @default.
• W1978253166 hasBestOaLocation W19782531661 @default.
• W1978253166 hasConcept C114851261 @default.
• W1978253166 hasConcept C126322002 @default.
• W1978253166 hasConcept C133936738 @default.
• W1978253166 hasConcept C185592680 @default.
• W1978253166 hasConcept C202751555 @default.
• W1978253166 hasConcept C2776694085 @default.
• W1978253166 hasConcept C2777071850 @default.
• W1978253166 hasConcept C2777132456 @default.
• W1978253166 hasConcept C2777229883 @default.
• W1978253166 hasConcept C2777292972 @default.
• W1978253166 hasConcept C2777366897 @default.
• W1978253166 hasConcept C2778707650 @default.
• W1978253166 hasConcept C2779548794 @default.
• W1978253166 hasConcept C2781021840 @default.
• W1978253166 hasConcept C2781064554 @default.
• W1978253166 hasConcept C2781303535 @default.
• W1978253166 hasConcept C55493867 @default.
• W1978253166 hasConcept C71924100 @default.
• W1978253166 hasConcept C86803240 @default.
• W1978253166 hasConcept C89423630 @default.
• W1978253166 hasConcept C98274493 @default.
• W1978253166 hasConceptScore W1978253166C114851261 @default.
• W1978253166 hasConceptScore W1978253166C126322002 @default.
• W1978253166 hasConceptScore W1978253166C133936738 @default.
• W1978253166 hasConceptScore W1978253166C185592680 @default.
• W1978253166 hasConceptScore W1978253166C202751555 @default.
• W1978253166 hasConceptScore W1978253166C2776694085 @default.
• W1978253166 hasConceptScore W1978253166C2777071850 @default.
• W1978253166 hasConceptScore W1978253166C2777132456 @default.
• W1978253166 hasConceptScore W1978253166C2777229883 @default.
• W1978253166 hasConceptScore W1978253166C2777292972 @default.
• W1978253166 hasConceptScore W1978253166C2777366897 @default.
• W1978253166 hasConceptScore W1978253166C2778707650 @default.
• W1978253166 hasConceptScore W1978253166C2779548794 @default.
• W1978253166 hasConceptScore W1978253166C2781021840 @default.
• W1978253166 hasConceptScore W1978253166C2781064554 @default.
• W1978253166 hasConceptScore W1978253166C2781303535 @default.
• W1978253166 hasConceptScore W1978253166C55493867 @default.
• W1978253166 hasConceptScore W1978253166C71924100 @default.
• W1978253166 hasConceptScore W1978253166C86803240 @default.
• W1978253166 hasConceptScore W1978253166C89423630 @default.
• W1978253166 hasConceptScore W1978253166C98274493 @default.
• W1978253166 hasIssue "9" @default.
• W1978253166 hasLocation W19782531661 @default.

• next