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- W1978260601 abstract "Recognition sites for the uptake of norepinephrine on adrenergic neurons in the brain and periphery were labeled with [3H]desipramine. The number of these uptake sites varied with the concentration of transmitter; depletion of norepinephrine with reserpine reduced the number of uptake sites, whereas increasing the concentration of norepinephrine induced by treatment with monoamine oxidase inhibitors raised the number of binding sites. These dynamic alterations in norepinephrine uptake recognition sites may regulate synaptic function homeostatically, providing less inactivation of reuptake when the synaptic concentration of the transmitter is low and increased inactivation when it is high." @default.
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- W1978260601 date "1983-05-06" @default.
- W1978260601 modified "2023-10-07" @default.
- W1978260601 title "Recognition Sites for Norepinephrine Uptake: Regulation by Neurotransmitter" @default.
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- W1978260601 doi "https://doi.org/10.1126/science.6301013" @default.
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