FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978269641> ?p ?o ?g. }

• W1978269641 endingPage "224" @default.
• W1978269641 startingPage "218" @default.
• W1978269641 abstract "We studied 7 patients with an acute motor axonal Guillain-Barré syndrome (GBS), manifested 5 to 15 days after parenteral injection of a commercial ganglioside preparation given for nonspecific pain syndromes. The serum IgG and IgM antibody response to ganglioside was studied serially and the recognition of epitopes on the peripheral nerves and motor end-plates was examined using biotinylated IgG extracted from the patient's serum. Sera from 8 patients treated with the same ganglioside preparation who did not develop neuropathy and from 25 patients with classic GBS never treated with gangliosides were studied concurrently. All patients with ganglioside-related GBS had a rather severe axonal degeneration, incomplete recovery, and high IgG, but not IgM, antiganglioside antibody titers, ranging from 1:320 to 1:10,240. Seven (28%) of the 25 GBS patients had IgG antibody titers, ranging from 1:160 to 1:10,240. None of the ganglioside-treated patients who did not develop GBS and none of the 50 disease control subjects had IgG GM1 antibodies. Purified IgG from the patients with high GM1 antibodies, but not from the others, recognized epitopes at the nodes of Ranvier and the distal motor nerve terminals at the end-plate. We conclude that exogenous ganglioside injections can be immunogenic, triggering IgG antiganglioside antibodies with specificity for motor nerve terminals. In some patients with axonal GBS such antibodies may be Marchkersor mediators of axonal involvement." @default.
• W1978269641 created "2016-06-24" @default.
• W1978269641 creator A5010336599 @default.
• W1978269641 creator A5041792199 @default.
• W1978269641 creator A5048129993 @default.
• W1978269641 creator A5050033206 @default.
• W1978269641 creator A5050480090 @default.
• W1978269641 creator A5090062651 @default.
• W1978269641 date "1995-08-01" @default.
• W1978269641 modified "2023-10-16" @default.
• W1978269641 title "Acute axonal Guillain-Barré syndrome with IgG antibodies against motor axons following parenteral gangliosides" @default.
• W1978269641 cites W1579107359 @default.
• W1978269641 cites W1974879497 @default.
• W1978269641 cites W1975873522 @default.
• W1978269641 cites W1980040627 @default.
• W1978269641 cites W1981037561 @default.
• W1978269641 cites W1988133312 @default.
• W1978269641 cites W1989580390 @default.
• W1978269641 cites W1991541707 @default.
• W1978269641 cites W1993608307 @default.
• W1978269641 cites W1995490372 @default.
• W1978269641 cites W1997531101 @default.
• W1978269641 cites W2003464363 @default.
• W1978269641 cites W2010549157 @default.
• W1978269641 cites W2013745539 @default.
• W1978269641 cites W2027276520 @default.
• W1978269641 cites W2035252775 @default.
• W1978269641 cites W2040867895 @default.
• W1978269641 cites W2042290376 @default.
• W1978269641 cites W2043176760 @default.
• W1978269641 cites W2050307985 @default.
• W1978269641 cites W2063109954 @default.
• W1978269641 cites W2065807871 @default.
• W1978269641 cites W2066498754 @default.
• W1978269641 cites W2078071482 @default.
• W1978269641 cites W2083576482 @default.
• W1978269641 cites W2085970433 @default.
• W1978269641 cites W2094978761 @default.
• W1978269641 cites W2097564959 @default.
• W1978269641 cites W2105267334 @default.
• W1978269641 cites W2107439279 @default.
• W1978269641 cites W2118637799 @default.
• W1978269641 cites W2118832722 @default.
• W1978269641 cites W2136295686 @default.
• W1978269641 cites W2163550872 @default.
• W1978269641 cites W2332365244 @default.
• W1978269641 cites W4256148706 @default.
• W1978269641 doi "https://doi.org/10.1002/ana.410380214" @default.
• W1978269641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7654069" @default.
• W1978269641 hasPublicationYear "1995" @default.
• W1978269641 type Work @default.
• W1978269641 sameAs 1978269641 @default.
• W1978269641 citedByCount "171" @default.
• W1978269641 countsByYear W19782696412012 @default.
• W1978269641 countsByYear W19782696412013 @default.
• W1978269641 countsByYear W19782696412014 @default.
• W1978269641 countsByYear W19782696412015 @default.
• W1978269641 countsByYear W19782696412017 @default.
• W1978269641 countsByYear W19782696412018 @default.
• W1978269641 countsByYear W19782696412019 @default.
• W1978269641 countsByYear W19782696412020 @default.
• W1978269641 countsByYear W19782696412021 @default.
• W1978269641 countsByYear W19782696412022 @default.
• W1978269641 countsByYear W19782696412023 @default.
• W1978269641 crossrefType "journal-article" @default.
• W1978269641 hasAuthorship W1978269641A5010336599 @default.
• W1978269641 hasAuthorship W1978269641A5041792199 @default.
• W1978269641 hasAuthorship W1978269641A5048129993 @default.
• W1978269641 hasAuthorship W1978269641A5050033206 @default.
• W1978269641 hasAuthorship W1978269641A5050480090 @default.
• W1978269641 hasAuthorship W1978269641A5090062651 @default.
• W1978269641 hasConcept C105702510 @default.
• W1978269641 hasConcept C118552586 @default.
• W1978269641 hasConcept C142724271 @default.
• W1978269641 hasConcept C159654299 @default.
• W1978269641 hasConcept C195616568 @default.
• W1978269641 hasConcept C203014093 @default.
• W1978269641 hasConcept C21715850 @default.
• W1978269641 hasConcept C2775912687 @default.
• W1978269641 hasConcept C2776553844 @default.
• W1978269641 hasConcept C2777331542 @default.
• W1978269641 hasConcept C2778691916 @default.
• W1978269641 hasConcept C2780052305 @default.
• W1978269641 hasConcept C2780898057 @default.
• W1978269641 hasConcept C2781200757 @default.
• W1978269641 hasConcept C522805319 @default.
• W1978269641 hasConcept C55493867 @default.
• W1978269641 hasConcept C71924100 @default.
• W1978269641 hasConcept C86803240 @default.
• W1978269641 hasConceptScore W1978269641C105702510 @default.
• W1978269641 hasConceptScore W1978269641C118552586 @default.
• W1978269641 hasConceptScore W1978269641C142724271 @default.
• W1978269641 hasConceptScore W1978269641C159654299 @default.
• W1978269641 hasConceptScore W1978269641C195616568 @default.
• W1978269641 hasConceptScore W1978269641C203014093 @default.
• W1978269641 hasConceptScore W1978269641C21715850 @default.
• W1978269641 hasConceptScore W1978269641C2775912687 @default.
• W1978269641 hasConceptScore W1978269641C2776553844 @default.

• next