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- W1978290247 abstract "Sixteen 2-azetidinones were designed and synthesized as cholesterol absorption inhibitors. The length of C-3 side chain was modified to four atoms by introducing ester or amide linkage to investigate further structure-activity relationships. The target compounds exhibited different cholesterol absorption inhibition activities, some of which were promising. Keywords: 2-Azetidinone, Cholesterol absorption inhibitor, NPC1L1, Ezetimibe, Bioactivities, Structure-activity relationship" @default.
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- W1978290247 date "2009-09-01" @default.
- W1978290247 modified "2023-09-23" @default.
- W1978290247 title "Synthesis and Bioactivities of 2-Azetidinones as Cholesterol Absorption Inhibitors" @default.
- W1978290247 doi "https://doi.org/10.2174/157018009789057562" @default.
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