FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978299204> ?p ?o ?g. }

• W1978299204 endingPage "H69" @default.
• W1978299204 startingPage "H62" @default.
• W1978299204 abstract "We investigated to what extent maximal ventricular elastance (E(max)) is dynamically controlled by the arterial baroreflex and force-frequency relation in conscious dogs and to what extent these mechanisms are attenuated after the induction of heart failure (HF). We mathematically analyzed spontaneous beat-to-beat hemodynamic variability. First, we estimated E(max) for each beat during a baseline period using the ventricular unstressed volume determined with the traditional multiple beat method during vena cava occlusion. We then jointly identified the transfer functions (system gain value and time delay per frequency) relating beat-to-beat fluctuations in arterial blood pressure (ABP) to E(max) (ABP-->E(max)) and beat-to-beat fluctuations in heart rate (HR) to E(max) (HR-->E(max)) to characterize the dynamic properties of the arterial baroreflex and force-frequency relation, respectively. During the control condition, the ABP-->E(max) transfer function revealed that ABP perturbations caused opposite direction E(max) changes with a gain value of -0.023 +/- 0.012 ml(-1), whereas the HR-->E(max) transfer function indicated that HR alterations caused same direction E(max) changes with a gain value of 0.013 +/- 0.005 mmHg.ml(-1).(beats/min)(-1). Both transfer functions behaved as low-pass filters. However, the ABP-->E(max) transfer function was more sluggish than the HR-->E(max) transfer function with overall time constants (indicator of full system response time to a sudden input change) of 11.2 +/- 2.8 and 1.7 +/- 0.5 s (P < 0.05), respectively. During the HF condition, the ABP-->E(max) and HR-->E(max) transfer functions were markedly depressed with gain values reduced to -0.0002 +/- 0.007 ml(-1) and -0.001 +/- 0.004 mmHg.ml(-1).(beats/min)(-1) (P < 0.1). E(max) is rapidly and significantly controlled at rest, but this modulation is virtually abolished in HF." @default.
• W1978299204 created "2016-06-24" @default.
• W1978299204 creator A5026968678 @default.
• W1978299204 creator A5045168992 @default.
• W1978299204 creator A5046159339 @default.
• W1978299204 creator A5046354867 @default.
• W1978299204 creator A5056440445 @default.
• W1978299204 creator A5076698656 @default.
• W1978299204 creator A5085084737 @default.
• W1978299204 date "2010-07-01" @default.
• W1978299204 modified "2023-10-16" @default.
• W1978299204 title "Dynamic control of maximal ventricular elastance via the baroreflex and force-frequency relation in awake dogs before and after pacing-induced heart failure" @default.
• W1978299204 cites W1789109696 @default.
• W1978299204 cites W1813248427 @default.
• W1978299204 cites W1829725583 @default.
• W1978299204 cites W1870743288 @default.
• W1978299204 cites W1924275791 @default.
• W1978299204 cites W1963721828 @default.
• W1978299204 cites W1966308708 @default.
• W1978299204 cites W1969197181 @default.
• W1978299204 cites W1969526499 @default.
• W1978299204 cites W1972370207 @default.
• W1978299204 cites W1973040683 @default.
• W1978299204 cites W1980673882 @default.
• W1978299204 cites W1981963153 @default.
• W1978299204 cites W1985185938 @default.
• W1978299204 cites W1997150558 @default.
• W1978299204 cites W2015246184 @default.
• W1978299204 cites W2021655220 @default.
• W1978299204 cites W2043405908 @default.
• W1978299204 cites W2044110796 @default.
• W1978299204 cites W2054407243 @default.
• W1978299204 cites W2057486798 @default.
• W1978299204 cites W2061272478 @default.
• W1978299204 cites W2071947027 @default.
• W1978299204 cites W2079879840 @default.
• W1978299204 cites W2081590661 @default.
• W1978299204 cites W2082258689 @default.
• W1978299204 cites W2088568206 @default.
• W1978299204 cites W2094668345 @default.
• W1978299204 cites W2099611466 @default.
• W1978299204 cites W2105249291 @default.
• W1978299204 cites W2109338186 @default.
• W1978299204 cites W2113072876 @default.
• W1978299204 cites W2114876661 @default.
• W1978299204 cites W2143703067 @default.
• W1978299204 cites W2158486075 @default.
• W1978299204 cites W2166303436 @default.
• W1978299204 cites W2174842019 @default.
• W1978299204 cites W2179736300 @default.
• W1978299204 cites W2254526050 @default.
• W1978299204 cites W2330551898 @default.
• W1978299204 cites W339703 @default.
• W1978299204 doi "https://doi.org/10.1152/ajpheart.00922.2009" @default.
• W1978299204 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2904132" @default.
• W1978299204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20435845" @default.
• W1978299204 hasPublicationYear "2010" @default.
• W1978299204 type Work @default.
• W1978299204 sameAs 1978299204 @default.
• W1978299204 citedByCount "8" @default.
• W1978299204 countsByYear W19782992042013 @default.
• W1978299204 countsByYear W19782992042014 @default.
• W1978299204 countsByYear W19782992042015 @default.
• W1978299204 countsByYear W19782992042019 @default.
• W1978299204 countsByYear W19782992042020 @default.
• W1978299204 countsByYear W19782992042022 @default.
• W1978299204 crossrefType "journal-article" @default.
• W1978299204 hasAuthorship W1978299204A5026968678 @default.
• W1978299204 hasAuthorship W1978299204A5045168992 @default.
• W1978299204 hasAuthorship W1978299204A5046159339 @default.
• W1978299204 hasAuthorship W1978299204A5046354867 @default.
• W1978299204 hasAuthorship W1978299204A5056440445 @default.
• W1978299204 hasAuthorship W1978299204A5076698656 @default.
• W1978299204 hasAuthorship W1978299204A5085084737 @default.
• W1978299204 hasBestOaLocation W19782992042 @default.
• W1978299204 hasConcept C121332964 @default.
• W1978299204 hasConcept C126322002 @default.
• W1978299204 hasConcept C164705383 @default.
• W1978299204 hasConcept C178853913 @default.
• W1978299204 hasConcept C189809214 @default.
• W1978299204 hasConcept C191237925 @default.
• W1978299204 hasConcept C24890656 @default.
• W1978299204 hasConcept C2777953023 @default.
• W1978299204 hasConcept C2780729457 @default.
• W1978299204 hasConcept C42219234 @default.
• W1978299204 hasConcept C534529494 @default.
• W1978299204 hasConcept C71924100 @default.
• W1978299204 hasConcept C84393581 @default.
• W1978299204 hasConceptScore W1978299204C121332964 @default.
• W1978299204 hasConceptScore W1978299204C126322002 @default.
• W1978299204 hasConceptScore W1978299204C164705383 @default.
• W1978299204 hasConceptScore W1978299204C178853913 @default.
• W1978299204 hasConceptScore W1978299204C189809214 @default.
• W1978299204 hasConceptScore W1978299204C191237925 @default.
• W1978299204 hasConceptScore W1978299204C24890656 @default.
• W1978299204 hasConceptScore W1978299204C2777953023 @default.
• W1978299204 hasConceptScore W1978299204C2780729457 @default.
• W1978299204 hasConceptScore W1978299204C42219234 @default.

• next