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- W1978304986 abstract "The most successful biological agent in insect control is Bacillus thuringiensis (Bt), a Gram positive, rod shaped, and aerobic spore forming, soil bacterium producing crystalline proteins (endotoxins) that have insecticidal properties. When ingested by the insect, the crystal proteins undergo activation in the insect gut under the influence of an alkaline pH and gut proteases and become active toxins that bind to the brush border membrane vesicles of the midgut epithelium cells and exert their toxicity by forming lytic pores. Classification of Cry proteins is based on homology of amino acids. The host range of Bt has expanded considerably in recent years due to extensive screening programs and makes use of the in vivo genetic recombination property. Cloned Bt toxin genes were introduced into a number of microbial hosts to create more stable and/or compatible agents for toxin delivery but the most effective delivery system for Bt toxins is transgenic plants. An important feature of such a system is that only insects eating the crop are exposed to the toxin. Genes encoding for Bt δ-endotoxins have been deployed in a wide range of crop plants with considerable success since the mid-1990s. However, it is pertinent to consider the relative environmental and mammalian safety of Bt strains compared with other pesticides used against the same pests." @default.
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- W1978304986 date "1970-01-01" @default.
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- W1978304986 title "Presence of flagellar antigenic subfactors in serotype 3 of Bacillus thuringiensis" @default.
- W1978304986 doi "https://doi.org/10.1016/0022-2011(70)90113-8" @default.
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