Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978314710> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1978314710 endingPage "1037" @default.
- W1978314710 startingPage "1030" @default.
- W1978314710 abstract "Widespread use of adjusted low-dose warfarin has been limited by the inconvenience of outpatient laboratory monitoring and the perceived risk of bleeding complications. We sought to determine if the dose of warfarin could be lowered safely even further, eliminating the need for laboratory monitoring and lowering the complication rate. Two hundred forty-five Patients undergoing primary total joint arthroplasty (n = 245) were randomized prospectively to adjusted low-dose warfarin (international normalized ratio [INR], 1.4-1.8) or fixed minidose warfarin (2 mg daily, regardless of INR) before hospital discharge. Prophylaxis continued for 6 weeks, with twice-weekly laboratory monitoring. Patients were followed for bleeding, thromboembolic events, and minor reported complications of warfarin therapy. With the numbers available, the rates of thromboembolic and bleeding events were not significantly different using equivalence analysis. Of patients in the fixed group, 8% had INRs >3.1, necessitating a decrease in dosage to 1 mg. Although such a fixed-dose protocol may simplify outpatient prophylaxis, intermittent monitoring still would be required because a subset of patients achieve a moderate level of anticoagulation and would be at risk for bleeding complications." @default.
- W1978314710 created "2016-06-24" @default.
- W1978314710 creator A5007595354 @default.
- W1978314710 creator A5010623364 @default.
- W1978314710 creator A5035412354 @default.
- W1978314710 creator A5066559368 @default.
- W1978314710 creator A5076278772 @default.
- W1978314710 creator A5088259763 @default.
- W1978314710 date "2001-12-01" @default.
- W1978314710 modified "2023-09-26" @default.
- W1978314710 title "Fixed minidose versus-adjusted low-dose warfarin after total joint arthroplasty" @default.
- W1978314710 cites W136838112 @default.
- W1978314710 cites W1598490706 @default.
- W1978314710 cites W1819664549 @default.
- W1978314710 cites W1901279264 @default.
- W1978314710 cites W1908679943 @default.
- W1978314710 cites W1916215700 @default.
- W1978314710 cites W1969404715 @default.
- W1978314710 cites W1969443491 @default.
- W1978314710 cites W1971522207 @default.
- W1978314710 cites W2001082320 @default.
- W1978314710 cites W2001411232 @default.
- W1978314710 cites W2012947624 @default.
- W1978314710 cites W2016206184 @default.
- W1978314710 cites W2020744412 @default.
- W1978314710 cites W2029826104 @default.
- W1978314710 cites W2040111834 @default.
- W1978314710 cites W2059680801 @default.
- W1978314710 cites W2066199886 @default.
- W1978314710 cites W2067670780 @default.
- W1978314710 cites W2071233061 @default.
- W1978314710 cites W2151774137 @default.
- W1978314710 cites W2158607231 @default.
- W1978314710 cites W2165088592 @default.
- W1978314710 cites W2173203919 @default.
- W1978314710 cites W2173206763 @default.
- W1978314710 cites W2174470220 @default.
- W1978314710 cites W2186530970 @default.
- W1978314710 cites W2196874047 @default.
- W1978314710 cites W2265007974 @default.
- W1978314710 cites W2286696002 @default.
- W1978314710 cites W2404957053 @default.
- W1978314710 cites W2418213914 @default.
- W1978314710 cites W2419582510 @default.
- W1978314710 cites W4299351781 @default.
- W1978314710 doi "https://doi.org/10.1054/arth.2001.27688" @default.
- W1978314710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11740759" @default.
- W1978314710 hasPublicationYear "2001" @default.
- W1978314710 type Work @default.
- W1978314710 sameAs 1978314710 @default.
- W1978314710 citedByCount "18" @default.
- W1978314710 countsByYear W19783147102012 @default.
- W1978314710 countsByYear W19783147102013 @default.
- W1978314710 countsByYear W19783147102014 @default.
- W1978314710 countsByYear W19783147102015 @default.
- W1978314710 crossrefType "journal-article" @default.
- W1978314710 hasAuthorship W1978314710A5007595354 @default.
- W1978314710 hasAuthorship W1978314710A5010623364 @default.
- W1978314710 hasAuthorship W1978314710A5035412354 @default.
- W1978314710 hasAuthorship W1978314710A5066559368 @default.
- W1978314710 hasAuthorship W1978314710A5076278772 @default.
- W1978314710 hasAuthorship W1978314710A5088259763 @default.
- W1978314710 hasConcept C126322002 @default.
- W1978314710 hasConcept C141071460 @default.
- W1978314710 hasConcept C2776301958 @default.
- W1978314710 hasConcept C2779161974 @default.
- W1978314710 hasConcept C42219234 @default.
- W1978314710 hasConcept C71924100 @default.
- W1978314710 hasConcept C81182388 @default.
- W1978314710 hasConceptScore W1978314710C126322002 @default.
- W1978314710 hasConceptScore W1978314710C141071460 @default.
- W1978314710 hasConceptScore W1978314710C2776301958 @default.
- W1978314710 hasConceptScore W1978314710C2779161974 @default.
- W1978314710 hasConceptScore W1978314710C42219234 @default.
- W1978314710 hasConceptScore W1978314710C71924100 @default.
- W1978314710 hasConceptScore W1978314710C81182388 @default.
- W1978314710 hasIssue "8" @default.
- W1978314710 hasLocation W19783147101 @default.
- W1978314710 hasLocation W19783147102 @default.
- W1978314710 hasOpenAccess W1978314710 @default.
- W1978314710 hasPrimaryLocation W19783147101 @default.
- W1978314710 hasRelatedWork W2002120878 @default.
- W1978314710 hasRelatedWork W2003938723 @default.
- W1978314710 hasRelatedWork W2047967234 @default.
- W1978314710 hasRelatedWork W2083103840 @default.
- W1978314710 hasRelatedWork W2118496982 @default.
- W1978314710 hasRelatedWork W2369768841 @default.
- W1978314710 hasRelatedWork W2439875401 @default.
- W1978314710 hasRelatedWork W2889182102 @default.
- W1978314710 hasRelatedWork W4238867864 @default.
- W1978314710 hasRelatedWork W2525756941 @default.
- W1978314710 hasVolume "16" @default.
- W1978314710 isParatext "false" @default.
- W1978314710 isRetracted "false" @default.
- W1978314710 magId "1978314710" @default.
- W1978314710 workType "article" @default.