FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1978341502> ?p ?o ?g. }

• W1978341502 endingPage "332" @default.
• W1978341502 startingPage "323" @default.
• W1978341502 abstract "In the present study we evaluated the involvement of l-arginine/nitric oxide (NO)/cGMP pathway in the antidepressant-like effects of acute lithium administration in the mouse forced swimming test (FST). Lithium, at 30 and 100 mg/kg, significantly reduced the immobility times of mice in the FST, whereas at lower doses (0.5, 5 and 10 mg/kg) had no effect on the immobility time. The NO synthase (NOS) inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME), at 10 and 30 mg/kg, and the selective neuronal NOS inhibitor N(omega)-propyl-L-arginine (L-NPA), at 5 and 15 mg/kg, had no significant effects on the FST, whereas they significantly decreased the immobility time at 100 and 30 mg/kg, respectively. Combination of non-effective dose of lithium (10 mg/kg) with low doses of L-NAME (30 mg/kg) or L-NPA (15 mg/kg) significantly reduced the immobility times in the FST. Moreover, the guanylyl cyclase inhibitor ODQ at 50 mg/kg significantly decreased the immobility time of mice, whereas it had not significant effects on the FST at 2, 10 and 20 mg/kg. Combination of lithium (10 mg/kg) with 20 mg/kg ODQ significantly decreased the immobility times in the FST. Non-effective doses of L-arginine (750 mg/kg) or sildenafil (5 mg/kg) significantly reversed the antidepressant-like effect of 30 mg/kg lithium in the FST. Neither of the drugs had effect on the locomotor activity. These data indicate the involvement of L-arginine/NO/cGMP pathway in the antidepressant-like effect of lithium in the mouse FST and also might suggest the concurrent administration of NOS inhibitors and lithium as an appropriate strategy for treatment of depression." @default.
• W1978341502 created "2016-06-24" @default.
• W1978341502 creator A5010167618 @default.
• W1978341502 creator A5023342808 @default.
• W1978341502 creator A5034729928 @default.
• W1978341502 creator A5041081626 @default.
• W1978341502 creator A5051922970 @default.
• W1978341502 creator A5082553019 @default.
• W1978341502 date "2008-05-01" @default.
• W1978341502 modified "2023-10-03" @default.
• W1978341502 title "Nitric oxide involvement in the antidepressant-like effects of acute lithium administration in the mouse forced swimming test" @default.
• W1978341502 cites W109954717 @default.
• W1978341502 cites W1486793005 @default.
• W1978341502 cites W1893156402 @default.
• W1978341502 cites W1965371574 @default.
• W1978341502 cites W1966785468 @default.
• W1978341502 cites W1967230695 @default.
• W1978341502 cites W1970022478 @default.
• W1978341502 cites W1973534109 @default.
• W1978341502 cites W1979420282 @default.
• W1978341502 cites W1980384268 @default.
• W1978341502 cites W1982037539 @default.
• W1978341502 cites W1982507661 @default.
• W1978341502 cites W1982943052 @default.
• W1978341502 cites W1986803960 @default.
• W1978341502 cites W1990536638 @default.
• W1978341502 cites W1991412103 @default.
• W1978341502 cites W1993342677 @default.
• W1978341502 cites W1997091817 @default.
• W1978341502 cites W1997093700 @default.
• W1978341502 cites W1999183223 @default.
• W1978341502 cites W2007083769 @default.
• W1978341502 cites W2008578135 @default.
• W1978341502 cites W2012207919 @default.
• W1978341502 cites W2015779369 @default.
• W1978341502 cites W2019465027 @default.
• W1978341502 cites W2021476447 @default.
• W1978341502 cites W2024378887 @default.
• W1978341502 cites W2025406984 @default.
• W1978341502 cites W2026218601 @default.
• W1978341502 cites W2029098829 @default.
• W1978341502 cites W2030703893 @default.
• W1978341502 cites W2031843542 @default.
• W1978341502 cites W2044069216 @default.
• W1978341502 cites W2044239520 @default.
• W1978341502 cites W2049031623 @default.
• W1978341502 cites W2050677124 @default.
• W1978341502 cites W2051138366 @default.
• W1978341502 cites W2052894434 @default.
• W1978341502 cites W2052911276 @default.
• W1978341502 cites W2070677737 @default.
• W1978341502 cites W2071596974 @default.
• W1978341502 cites W2072482720 @default.
• W1978341502 cites W2081884263 @default.
• W1978341502 cites W2084419154 @default.
• W1978341502 cites W2084686735 @default.
• W1978341502 cites W2084937886 @default.
• W1978341502 cites W2085579130 @default.
• W1978341502 cites W2087314928 @default.
• W1978341502 cites W2090829498 @default.
• W1978341502 cites W2092887810 @default.
• W1978341502 cites W2095181899 @default.
• W1978341502 cites W2111478092 @default.
• W1978341502 cites W2122561721 @default.
• W1978341502 cites W2126322838 @default.
• W1978341502 cites W2131167630 @default.
• W1978341502 cites W2133627256 @default.
• W1978341502 cites W2147713091 @default.
• W1978341502 cites W2153392151 @default.
• W1978341502 cites W2155709733 @default.
• W1978341502 cites W2159923189 @default.
• W1978341502 cites W2324024854 @default.
• W1978341502 cites W4250845827 @default.
• W1978341502 doi "https://doi.org/10.1016/j.euroneuro.2007.07.011" @default.
• W1978341502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17728109" @default.
• W1978341502 hasPublicationYear "2008" @default.
• W1978341502 type Work @default.
• W1978341502 sameAs 1978341502 @default.
• W1978341502 citedByCount "91" @default.
• W1978341502 countsByYear W19783415022012 @default.
• W1978341502 countsByYear W19783415022013 @default.
• W1978341502 countsByYear W19783415022014 @default.
• W1978341502 countsByYear W19783415022015 @default.
• W1978341502 countsByYear W19783415022016 @default.
• W1978341502 countsByYear W19783415022017 @default.
• W1978341502 countsByYear W19783415022018 @default.
• W1978341502 countsByYear W19783415022019 @default.
• W1978341502 countsByYear W19783415022020 @default.
• W1978341502 countsByYear W19783415022021 @default.
• W1978341502 countsByYear W19783415022022 @default.
• W1978341502 countsByYear W19783415022023 @default.
• W1978341502 crossrefType "journal-article" @default.
• W1978341502 hasAuthorship W1978341502A5010167618 @default.
• W1978341502 hasAuthorship W1978341502A5023342808 @default.
• W1978341502 hasAuthorship W1978341502A5034729928 @default.
• W1978341502 hasAuthorship W1978341502A5041081626 @default.
• W1978341502 hasAuthorship W1978341502A5051922970 @default.
• W1978341502 hasAuthorship W1978341502A5082553019 @default.

• next