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• W1978343886 abstract "Since late vessel failure has been speculated as a significant limitation of vascular brachytherapy (VBT), we conducted a prospective clinical evaluation at 6, 12, 24, 36 and 60 months follow-up after irradiation with 90Sr/90Y for in-stent restenosis (ISR) regardless of the patient's symptomatic status. Complete five-year follow-up is reported for 104 consecutive patients. The cumulative rate of death was 13.5% (6 months: 0.96%; 12 months: 2.88%; 24 months: 4.81%; 36 months: 7.69%), of acute myocardial infarction 4.81% (2.88%; 4.81%; 4.81%; 4.81%), of late thrombotic occlusion 4.81% (3.85%; 4.81%; 4.81%; 4.81%), of target lesion revascularization (TLR) 27.9% (8.65%; 12.5%; 17.3%; 21.2%), of target vessel revascularization (TVR) 43.3% (12.5%; 19.2%; 22.1%; 29.8%), and of all major adverse cardiovascular events (MACE) 61.5% (16.3%; 26.9%; 31.7%; 42.3%), respectively. Considered that the annual incidence of TVR after the first year following drug-eluting stenting for in-stent restenosis has been reported as approximately 3% per year, an incidence of 5.8% per year following VBT of our study population clearly indicates a more pronounced, delayed and, even in the fifth year after the index procedure, ongoing restenotic process following beta-irradiation of in-stent restenotic |lesions associated with clinically relevant adverse cardiovascular events." @default.
• W1978343886 created "2016-06-24" @default.
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• W1978343886 date "2011-01-18" @default.
• W1978343886 modified "2023-09-23" @default.
• W1978343886 title "Late and very late catch-up after90Sr/90Y beta-irradiation for the treatment of coronary in-stent restenosis" @default.
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• W1978343886 doi "https://doi.org/10.3109/17482941.2010.532221" @default.
• W1978343886 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21244228" @default.
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