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• W1978358623 abstract "The revised International Prognostic Scoring System (IPSS-R) was developed in a cohort of untreated myelodysplastic syndromes (MDS) patients. A French Prognostic Scoring System (FPSS) was recently reported to identify differential survival among azacitidine-treated patients with high-risk MDS. We applied the FPSS and IPSS-R to 150 patients previously randomized to azacitidine monotherapy or a combination of azacitidine with entinostat (a histone deacetylase inhibitor). Neither score predicted response but both discriminated patients with different overall survival (OS; median OS, FPSS: 9·7, 14·7, and 25·3 months, P = 0·018; IPSS-R: 12·5, 11·3, 20·8, and 36 months, P = 0·005). Statistical analysis suggested no improvement in OS prediction for the FPSS over the IPSS-R in azacitidine-treated patients." @default.
• W1978358623 created "2016-06-24" @default.
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• W1978358623 date "2014-04-09" @default.
• W1978358623 modified "2023-09-27" @default.
• W1978358623 title "Comparison of the prognostic utility of the revised International Prognostic Scoring System and the French Prognostic Scoring System in azacitidine-treated patients with myelodysplastic syndromes" @default.
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• W1978358623 doi "https://doi.org/10.1111/bjh.12884" @default.
• W1978358623 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4299460" @default.
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