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- W1978375770 abstract "The actions of the excitatory amino acid ibotenate were investigated in postnatal rat hippocampal neurons. In neurons voltage clamped at negative membrane potentials using low-chloride internal solutions, ibotenate responses consist of an inward cationic current and two outward currents. The inward current is inhibited by 2-amino-5-phosphonovalerate (APV), a selective N-methyl-D-aspartate (NMDA) antagonist. The two outward currents consist of a picrotoxin and bicuculline-sensitive chloride current and a slowly developing calcium activated potassium current. The bicuculline sensitive current appears to be the product of contamination of ibotenate samples with the gamma-aminobutyric acid (GABA) agonist muscimol and not the result of a direct action of ibotenate." @default.
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- W1978375770 date "1989-08-01" @default.
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- W1978375770 title "Complex responses activated by ibotenate in postnatal rat hippocampal neurons" @default.
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- W1978375770 doi "https://doi.org/10.1016/0006-8993(89)90163-7" @default.
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