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- W1978391063 abstract "Intravenous injection of purified tetanus toxin(1000-0.06 μg) killed mice within minutes(20–450 min), causing flaccid paralysis indistinguishable from that in botulinum intoxication: a linear relation was found between the log of the toxin dose and that of death time(survival time). The dose and route dependences of the manifestations of the spastic paralysis typical of classical tetanus and of the acute botulinum-like flaccid paralysis were studied in relation to the death time. Treatment of the toxin with trypsin or gangliosides did not affect its acute botulinum-like toxicity. Theophylline delayed the time of acute death due to the botulinum-like intoxication in mice caused by tetanus toxin and provided some protection." @default.
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- W1978391063 date "1982-01-01" @default.
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- W1978391063 title "Acute botulinum-like intoxication by tetanus neurotoxin in mice" @default.
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- W1978391063 doi "https://doi.org/10.1016/0006-291x(82)90708-2" @default.
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