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- W1978394734 abstract "Abstract. Mercuric chloride introduced into the systemic circulation or directly into the renal artery in dogs leads to an immediate and lasting fall in renal blood flow. On arteriography severe cortical ischaemia is seen. These findings were studied in 32 animals. Renal vascular shut-down induced by mercuric chloride appears concentration dependent, and is not mediated by glomerular filtration. It is possible to protect the kidney from shut-down by an infusion of hyperosmolar mannitol given before mercuric chloride. This suggests that the ‘no-reflow phenomenon’, already documented in the ischaemic kidney and brain, has a counterpart in mercury induced acute renal failure. Endothelial cell swelling may be an important primary vascular disorder underlying many acute renal failure states." @default.
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- W1978394734 date "1974-02-01" @default.
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- W1978394734 title "Mercury-Induced Renal Vascular Shut-Down: Observations in Experimental Acute Renal Failure" @default.
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- W1978394734 doi "https://doi.org/10.1111/j.1365-2362.1974.tb00364.x" @default.
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