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- W1978395898 abstract "We report here that a point mutation in the gene which encodes the heterochromatin-specific nonhistone chromosomal protein HP-1 in Drosophila melanogaster is associated with dominant suppression of position-effect variegation. The mutation, a G-to-A transition at the first nucleotide of the last intron, causes missplicing of the HP-1 mRNA. This suggests that heterochromatin-specific proteins play a central role in the gene suppression associated with heterochromatic position effects." @default.
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- W1978395898 date "1990-12-01" @default.
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- W1978395898 title "Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster." @default.
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- W1978395898 doi "https://doi.org/10.1073/pnas.87.24.9923" @default.
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